p53-mediated apoptosis prevents the accumulation of progenitor B cells and B-cell tumors. (Q45910544)

17 December 2017

title

p53-mediated apoptosis prevents the accumulation of progenitor B cells and B-cell tumors. (English)

1 reference

17 December 2017

author name string

T L Slatter

1

1 reference

17 December 2017

P Ganesan

2

1 reference

17 December 2017

C Holzhauer

3

1 reference

17 December 2017

R Mehta

4

1 reference

17 December 2017

C Rubio

5

1 reference

17 December 2017

G Williams

6

1 reference

17 December 2017

M Wilson

7

1 reference

17 December 2017

J A Royds

8

1 reference

17 December 2017

M A Baird

9

1 reference

17 December 2017

A W Braithwaite

10

1 reference

17 December 2017

publication date

25 September 2009

1 reference

17 December 2017

Cell Death & Differentiation

published in

1 reference

17 December 2017

volume

17

1 reference

17 December 2017

issue

3

1 reference

17 December 2017

page(s)

540-550

1 reference

17 December 2017

The presence of TP53 mutation at diagnosis of follicular lymphoma identifies a high-risk group of patients with shortened time to disease progression and poorer overall survival

cites work

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Mutations in the DNA-binding codons of TP53, which are associated with decreased expression of TRAILreceptor-2, predict for poor survival in diffuse large B-cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Tumor spectrum analysis in p53-mutant mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Live or let die: the cell's response to p53

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Restoration of p53 function leads to tumour regression in vivo

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

The proline-rich region of mouse p53 influences transactivation and apoptosis but is largely dispensable for these functions.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

A proline-rich motif in p53 is required for transactivation-independent growth arrest as induced by Gas1.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Mouse mutants reveal that putative protein interaction sites in the p53 proline-rich domain are dispensable for tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Interaction of γ-irradiation with two new antineoplastic agents, aziridinylbenzoquinone (AZQ) and 4′-(acridinylamino)methanesulfon-m-anisidide (AMSA), in murine tumors in vivo

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Use of a fluorescently labeled poly-caspase inhibitor for in vivo detection of apoptosis related to vascular-targeting agent arsenic trioxide for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

ASPP proteins specifically stimulate the apoptotic function of p53

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Tumor-derived mutations within the DNA-binding domain of p53 that phenotypically resemble the deletion of the proline-rich domain

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

The polyproline region of p53 is required to activate apoptosis but not growth arrest.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

The protean nature of cells in the B lymphocyte lineage

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Mutant mice without B lymphocyte follicles

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Essential role for p53-mediated transcription in E1A-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Blockade of death receptor-mediated pathways early in the signaling cascade coincides with distinct apoptosis resistance in cutaneous T-cell lymphoma cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Lack of T-cell receptor-induced signaling is crucial for CD95 ligand up-regulation and protects cutaneous T-cell lymphoma cells from activation-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Cotreatment with BCL-2 antagonist sensitizes cutaneous T-cell lymphoma to lethal action of HDAC7-Nur77-based mechanism.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Bad-deficient mice develop diffuse large B cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Short telomeres limit tumor progression in vivo by inducing senescence

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

CD19 regulates positive selection and maturation in B lymphopoiesis: lack of CD19 imposes developmental arrest of immature B cells and consequential stimulation of receptor editing

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Clinicopathologic significance of loss of CD19 expression in diffuse large B-cell lymphoma.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Loss of CD19 expression in B-cell neoplasms

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Selective loss of B-cell phenotype in lymphocyte predominant Hodgkin lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Diminished expression of CD19 in B-cell lymphomas

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.136

7 January 2021

Identifiers

DOI

10.1038/CDD.2009.136

1 reference

17 December 2017

Dimensions Publication ID

1019555745

0 references

1 reference

17 December 2017