Elevated Response to Type I IFN Enhances RANKL-Mediated Osteoclastogenesis in Usp18-Knockout Mice. (Q45948743)

18 December 2017

title

Elevated Response to Type I IFN Enhances RANKL-Mediated Osteoclastogenesis in Usp18-Knockout Mice. (English)

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18 December 2017

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6

Sung Hee Baek

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18 December 2017

Keun Il Kim

9

object named as

Keun Il Kim

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18 December 2017

Raok Jeon

5

object named as

Raok Jeon

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18 December 2017

author name string

Hwa Young Yim

1

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18 December 2017

Cheolkyu Park

2

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18 December 2017

Yong Deok Lee

3

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18 December 2017

Kei-Ichiro Arimoto

4

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18 December 2017

Dong-Er Zhang

7

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18 December 2017

Hong-Hee Kim

8

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18 December 2017

language of work or name

English

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publication date

25 March 2016

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18 December 2017

published in

Journal of Immunology

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18 December 2017

volume

196

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18 December 2017

issue

9

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18 December 2017

page(s)

3887-3895

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18 December 2017

Control of osteoblast function and regulation of bone mass

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Signaling crosstalk between RANKL and interferons in osteoclast differentiation

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Interplay between interferon and other cytokine systems in bone metabolism

21 January 2018

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Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

21 January 2018

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Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis.

21 January 2018

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The role of NFAT in osteoclast formation

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Interferon-stimulated gene 15 and the protein ISGylation system

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UBP43 (USP18) specifically removes ISG15 from conjugated proteins

21 January 2018

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Protein ISGylation modulates the JAK-STAT signaling pathway

21 January 2018

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Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection.

21 January 2018

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Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulating type I IFN signaling.

21 January 2018

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The mitochondrial pathway and reactive oxygen species are critical contributors to interferon-α/β-mediated apoptosis in Ubp43-deficient hematopoietic cells.

21 January 2018

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UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity

21 January 2018

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Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance

21 January 2018

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PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts.

21 January 2018

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SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1-dependent inflammatory arthritis

21 January 2018

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The level of hepatitis B virus replication is not affected by protein ISG15 modification but is reduced by inhibition of UBP43 (USP18) expression

21 January 2018

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Microarray analysis reveals that Type I interferon strongly increases the expression of immune-response related genes in Ubp43 (Usp18) deficient macrophages

21 January 2018

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Human osteoclasts express different CXC chemokines depending on cell culture substrate: molecular and immunocytochemical evidence of high levels of CXCL10 and CXCL12.

21 January 2018

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An in vivo genome wide gene expression study of circulating monocytes suggested GBP1, STAT1 and CXCL10 as novel risk genes for the differentiation of peak bone mass

21 January 2018

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RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β

21 January 2018

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c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling

21 January 2018

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The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

21 January 2018

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21 January 2018

Identifiers

DOI

10.4049/JIMMUNOL.1501496

1 reference

18 December 2017

PubMed ID

27016605

1 reference

18 December 2017