Electrostatic basis for bioenergetics. (Q46023362)

18 December 2017

title

Electrostatic basis for bioenergetics. (English)

1 reference

18 December 2017

4

Arieh Warshel

1 reference

18 December 2017

Avital Shurki

1

1 reference

18 December 2017

Marek Strajbl

series ordinal

2

1 reference

18 December 2017

Claudia N Schutz

series ordinal

3

1 reference

18 December 2017

language of work or name

English

0 references

publication date

1 January 2004

1 reference

18 December 2017

published in

Methods in Enzymology

1 reference

18 December 2017

volume

380

1 reference

18 December 2017

page(s)

52-84

1 reference

18 December 2017

Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Cytochrome c oxidase: structure and spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

The binding change mechanism for ATP synthase--some probabilities and possibilities

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Energy transduction in the F1 motor of ATP synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Computer simulations of enzyme catalysis: methods, progress, and insights

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

The depth of chemical time and the power of enzymes as catalysts.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Electrostatic origin of the catalytic power of enzymes and the role of preorganized active sites

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Selective stabilization of the chorismate mutase transition state by a positively charged hydrogen bond donor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Theoretical studies of enzymic reactions: dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Energetics of enzyme catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Calculations of antibody-antigen interactions: microscopic and semi-microscopic evaluation of the free energies of binding of phosphorylcholine analogs to McPC603

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Calculations of electrostatic interactions in biological systems and in solutions

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

On the Theory of Oxidation‐Reduction Reactions Involving Electron Transfer. I

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Computer simulation of the triosephosphate isomerase catalyzed reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Crystal structure of a lysozyme-tetrasaccharide lactone complex

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

A view at the millennium: the efficiency of enzymatic catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Dynamics of biochemical and biophysical reactions: insight from computer simulations

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

How much do enzymes really gain by restraining their reacting fragments?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Substrate conformational transitions in the active site of chorismate mutase: their role in the catalytic mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

The mechanism of catalysis of the chorismate to prephenate reaction by the Escherichia coli mutase enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Enzymes do what is expected (chalcone isomerase versus chorismate mutase).

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Just a near attack conformer for catalysis (chorismate to prephenate rearrangements in water, antibody, enzymes, and their mutants).

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Apparent NAC effect in chorismate mutase reflects electrostatic transition state stabilization

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Remarkable rate enhancement of orotidine 5'-monophosphate decarboxylase is due to transition-state stabilization rather than to ground-state destabilization.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Elucidating the nature of enzyme catalysis utilizing a new twist on an old methodology: quantum mechanical-free energy calculations on chemical reactions in enzymes and in aqueous solution

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

So do we understand how enzymes work?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Mechanisms of thiamine-catalyzed reactions. Decarboxylation of 2-(1-carboxy-l-hydroxyethyl)-3,4-dimethylthiazolium chloride

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

A proficient enzyme revisited: the predicted mechanism for orotidine monophosphate decarboxylase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Alternative view of enzyme reactions

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Non-enzymatic and enzymatic hydrolysis of alkyl halides: a haloalkane dehalogenation enzyme evolved to stabilize the gas-phase transition state of an SN2 displacement reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Crystal structure of the thiamin diphosphate-dependent enzyme pyruvate decarboxylase from the yeast Saccharomyces cerevisiae at 2.3 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Remarkable stabilization of zwitterionic intermediates may account for a billion-fold rate acceleration by thiamin diphosphate-dependent decarboxylases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

What about protein polarity?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Electrostatic effects in macromolecules: fundamental concepts and practical modeling

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Macroscopic models for studies of electrostatic interactions in proteins: limitations and applicability

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Computer simulations of enzyme catalysis: finding out what has been optimized by evolution.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Electrostatic stress in catalysis: Structure and mechanism of the enzyme orotidine monophosphate decarboxylase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Quantum mechanical methods for enzyme kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Catalytic proficiency: the unusual case of OMP decarboxylase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Combined QM/MM study of the mechanism and kinetic isotope effect of the nucleophilic substitution reaction in haloalkane dehalogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Atomic coordinates for subtilisin BPN′ (or Novo)

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Evaluation of catalytic free energies in genetically modified proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Free energy perturbation calculations on binding and catalysis after mutating Asn 155 in subtilisin

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Transition-state stabilization in the mechanism of tyrosyl-tRNA synthetase revealed by protein engineering

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Engineering subtilisin BPN' for site-specific proteolysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Low-barrier hydrogen bonds and enzymic catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

A low-barrier hydrogen bond in the catalytic triad of serine proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

The low barrier hydrogen bond in enzymatic catalysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Energy considerations show that low-barrier hydrogen bonds do not offer a catalytic advantage over ordinary hydrogen bonds

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

How do serine proteases really work?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

A low-barrier hydrogen bond in the catalytic triad of serine proteases? Theory versus experiment

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

A new concept for the mechanism of action of chymotrypsin: the role of the low-barrier hydrogen bond

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Energy transduction in ATP synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Transient accumulation of elastic energy in proton translocating ATP synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Simulations of ion current in realistic models of ion channels: the KcsA potassium channel

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

What are the dielectric "constants" of proteins and how to validate electrostatic models?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Calculations of enzymatic reactions: calculations of pKa, proton transfer reactions, and general acid catalysis reactions in enzymes.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Why nature chose phosphates

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

G proteins, effectors and GAPs: structure and mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Nucleoside triphosphate-binding proteins: different scaffolds to achieve phosphoryl transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Signal transduction pathways involving Ras. Mini review

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

On the mechanism of guanosine triphosphate hydrolysis in ras p21 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Why have mutagenesis studies not located the general base in ras p21

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Electrostatic control of GTP and GDP binding in the oncoprotein p21ras

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Mechanistic analysis of the observed linear free energy relationships in p21ras and related systems.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

How does GAP catalyze the GTPase reaction of Ras? A computer simulation study

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Structure of the photosynthetic reaction centre from Rhodobacter sphaeroides at 2.65 A resolution: cofactors and protein-cofactor interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Proton transfer in reaction centers from photosynthetic bacteria

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Conversion of light energy to electrostatic energy in the proton pump of Halobacterium halobium

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Permeation of ions across the potassium channel: Brownian dynamics studies

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Electrostatic control of the efficiency of light-induced electron transfer across membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

Protein Control of Redox Potentials of Ironminus signSulfur Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2980003-X

7 January 2021

10.1016/S0076-6879(04)80003-X

Identifiers

DOI

1 reference

18 December 2017

1 reference

18 December 2017