Transgenic mitochondrial superoxide dismutase and mitochondrially targeted catalase prevent antiretroviral-induced oxidative stress and cardiomyopathy. (Q46034270)

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scientific article published on 27 April 2009

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English	Transgenic mitochondrial superoxide dismutase and mitochondrially targeted catalase prevent antiretroviral-induced oxidative stress and cardiomyopathy.	scientific article published on 27 April 2009

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scholarly article

1 reference

Europe PubMed Central

18 December 2017

http://europepmc.org/abstract/MED/19398959

Transgenic mitochondrial superoxide dismutase and mitochondrially targeted catalase prevent antiretroviral-induced oxidative stress and cardiomyopathy. (English)

1 reference

Europe PubMed Central

18 December 2017

http://europepmc.org/abstract/MED/19398959

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author name string

James J Kohler

1

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Europe PubMed Central

18 December 2017

http://europepmc.org/abstract/MED/19398959

Ioan Cucoranu

2

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Europe PubMed Central

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http://europepmc.org/abstract/MED/19398959

Earl Fields

3

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Europe PubMed Central

18 December 2017

http://europepmc.org/abstract/MED/19398959

Elgin Green

4

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Europe PubMed Central

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http://europepmc.org/abstract/MED/19398959

Stanley He

5

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Europe PubMed Central

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http://europepmc.org/abstract/MED/19398959

Amy Hoying

6

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http://europepmc.org/abstract/MED/19398959

Rodney Russ

7

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Europe PubMed Central

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http://europepmc.org/abstract/MED/19398959

Allison Abuin

8

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Europe PubMed Central

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http://europepmc.org/abstract/MED/19398959

David Johnson

9

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Europe PubMed Central

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http://europepmc.org/abstract/MED/19398959

Seyed H Hosseini

10

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Europe PubMed Central

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http://europepmc.org/abstract/MED/19398959

C Michael Raper

11

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Europe PubMed Central

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http://europepmc.org/abstract/MED/19398959

William Lewis

12

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Europe PubMed Central

18 December 2017

http://europepmc.org/abstract/MED/19398959

publication date

27 April 2009

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18 December 2017

http://europepmc.org/abstract/MED/19398959

Laboratory Investigation

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http://europepmc.org/abstract/MED/19398959

89

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http://europepmc.org/abstract/MED/19398959

782-790

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http://europepmc.org/abstract/MED/19398959

7

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18 December 2017

http://europepmc.org/abstract/MED/19398959

https://scigraph.springernature.com/pub.10.1038/labinvest.2009.39

0 references

Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society-USA panel.

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21 January 2018

Cardiac dysfunction occurs in the HIV-1 transgenic mouse treated with zidovudine

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21 January 2018

Zidovudine-induced alterations in the heart and vascular smooth muscle of the rat.

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21 January 2018

Cardiac pathologic effects of azidothymidine (AZT) in Mg-deficient mice

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Myocardial Fas ligand expression increases susceptibility to AZT-induced cardiomyopathy

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Mitochondrial toxicity of antiviral drugs

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Nitrosative stress leads to protein glutathiolation, increased s-nitrosation, and up-regulation of peroxiredoxins in the heart

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21 January 2018

The importance of free radicals and catalytic metal ions in human diseases

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Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity

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Peroxisomes and oxidative stress

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The role of H 2 O 2 generation in perfused rat liver and the reaction of catalase compound I and hydrogen donors.

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The cellular production of hydrogen peroxide

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A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

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Overexpression of MnSOD protects against myocardial ischemia/reperfusion injury in transgenic mice.

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The Nature of Antioxidant Defense Mechanisms: A Lesson from Transgenic Studies

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Extension of murine life span by overexpression of catalase targeted to mitochondria

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Metalloporphyrin class of therapeutic catalytic antioxidants

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Requirement for superoxide in excitotoxic cell death.

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Combined antiretroviral therapy causes cardiomyopathy and elevates plasma lactate in transgenic AIDS mice

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Cocaine increases mortality and cardiac mass in a murine transgenic model of acquired immune deficiency syndrome

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21 January 2018

Mitochondrial myopathy caused by long-term zidovudine therapy

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21 January 2018

Role of reactive oxygen species and poly-ADP-ribose polymerase in the development of AZT-induced cardiomyopathy in rat.

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21 January 2018

Mitochondrial toxicity of nrti antiviral drugs: an integrated cellular perspective

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AZT induces oxidative damage to cardiac mitochondria: protective effect of vitamins C and E.

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21 January 2018

AZT treatment induces molecular and ultrastructural oxidative damage to muscle mitochondria. Prevention by antioxidant vitamins

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21 January 2018

Site-specific reduction of oxidative and lipid metabolism in adipose tissue of 3'-azido-3'-deoxythymidine-treated rats

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21 January 2018

Mechanistic explanation to the variable degradation behaviour of stavudine and zidovudine under hydrolytic, oxidative and photolytic conditions

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21 January 2018

Oxidative DNA damage induced by photodegradation products of 3(')-azido-3(')-deoxythymidine

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21 January 2018

HAART drugs induce oxidative stress in human endothelial cells and increase endothelial recruitment of mononuclear cells: exacerbation by inflammatory cytokines and amelioration by antioxidants

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21 January 2018

The keys of oxidative stress in acquired immune deficiency syndrome apoptosis.

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21 January 2018

Learning from failure: congestive heart failure in the postgenomic age

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21 January 2018

Zidovudine induces molecular, biochemical, and ultrastructural changes in rat skeletal muscle mitochondria

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21 January 2018

Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation

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21 January 2018

Reactive oxygen species production in energized cardiac mitochondria during hypoxia/reoxygenation: modulation by nitric oxide

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21 January 2018

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

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21 January 2018

Endotoxin challenge reduces aconitase activity in myocardial tissue

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21 January 2018

Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction

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21 January 2018

A new paradigm: manganese superoxide dismutase influences the production of H2O2 in cells and thereby their biological state.

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21 January 2018

Mitochondria: are they the seat of senescence?

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21 January 2018

Hydroperoxide metabolism in mammalian organs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histochemical and ultrastructural changes induced by zidovudine in mitochondria of rat cardiac muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of acetyl-l-carnitine against oxidative stress induced by antiretroviral drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

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Contribution of mitochondrial dysfunction and oxidative stress to cellular premature senescence induced by antiretroviral thymidine analogues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

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Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

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Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Some HIV antiretrovirals increase oxidative stress and alter chemokine, cytokine or adiponectin production in human adipocytes and macrophages.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SERCA overexpression reduces hydroxyl radical injury in murine myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nature of antioxidant defense mechanisms: a lesson from transgenic studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liposome-mediated augmentation of catalase in alveolar type II cells protects against H2O2 injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial ultrastructural and molecular changes induced by zidovudine in rat hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative DNA damage in fetal tissues after transplacental exposure to 3'-azido-3'-deoxythymidine (AZT)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of peroxiredoxins in regulating intracellular hydrogen peroxide and hydrogen peroxide-induced apoptosis in thyroid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of glutathione peroxidase attenuates myocardial remodeling and preserves diastolic function in diabetic heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase gamma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of mitochondrial peroxiredoxin-3 prevents left ventricular remodeling and failure after myocardial infarction in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19398959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/LABINVEST.2009.39

1 reference

Europe PubMed Central

18 December 2017

http://europepmc.org/abstract/MED/19398959

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1 reference

Europe PubMed Central

18 December 2017

http://europepmc.org/abstract/MED/19398959

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