Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells. (Q46070162)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19330025%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells (English)

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25 January 2020

5

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25 January 2020

author name string

H Li

1

1 reference

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25 January 2020

Y J Choi

2

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25 January 2020

M A Hanes

3

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25 January 2020

T Marple

4

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25 January 2020

P Hasty

6

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25 January 2020

language of work or name

English

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publication date

30 March 2009

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25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19330025%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

28

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25 January 2020

issue

16

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25 January 2020

page(s)

1875-1878

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Genotoxicity of streptonigrin: a review

25 January 2020

cites work

1 reference

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Ionizing radiation exposure results in up-regulation of Ku70 via a p53/ataxia-telangiectasia-mutated protein-dependent mechanism

31 March 2020

1 reference

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Role of non-homologous end joining (NHEJ) in maintaining genomic integrity

31 March 2020

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Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity.

31 March 2020

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DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

31 March 2020

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

31 March 2020

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Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

31 March 2020

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Mre11 and Ku70 interact in somatic cells, but are differentially expressed in early meiosis

31 March 2020

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Bax-inhibiting peptides derived from Ku70 and cell-penetrating pentapeptides

31 March 2020

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Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

31 March 2020

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Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

31 March 2020

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Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice

31 March 2020

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Ku80 deletion suppresses spontaneous tumors and induces a p53-mediated DNA damage response

31 March 2020

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Deletion of Ku80 causes early aging independent of chronic inflammation and Rag-1-induced DSBs

31 March 2020

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Ku80 and p53 suppress medulloblastoma that arise independent of Rag-1-induced DSBs.

31 March 2020

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Ku acts in a unique way at the mammalian telomere to prevent end joining

31 March 2020

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Ku70 can translocate to the nucleus independent of Ku80 translocation and DNA-PK autophosphorylation

31 March 2020

1 reference

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Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer

31 March 2020

1 reference

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Analysis of ku80-mutant mice and cells with deficient levels of p53

31 March 2020

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NF-kappaB p65 regulates nuclear translocation of Ku70 via degradation of heat shock cognate protein 70 in pancreatic acinar AR42J cells

31 March 2020

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A genotoxic screen: rapid analysis of cellular dose-response to a wide range of agents that either damage DNA or alter genome maintenance pathways

31 March 2020

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Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.

31 March 2020

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Ku80 autoantigen as a cellular coreceptor for human parvovirus B19 infection

31 March 2020

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Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

31 March 2020

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Transcriptional control of human p53-regulated genes

31 March 2020

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p95vav associates with the nuclear protein Ku-70

31 March 2020

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Interaction of human Ku70 with TRF2

31 March 2020

1 reference

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Human Ku70 interacts with heterochromatin protein 1alpha

31 March 2020

1 reference

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Deletion of Ku86 causes early onset of senescence in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.57

Identification of two domains of the p70 Ku protein mediating dimerization with p80 and DNA binding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.57

Isolation of Ku70-binding proteins (KUBs)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.57

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

31 March 2020

1 reference

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