Kinetics of the inflammatory response following intramuscular injection of aluminum adjuvant. (Q46288429)

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3 March 2020

title

Kinetics of the inflammatory response following intramuscular injection of aluminum adjuvant (English)

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2

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3 March 2020

author name string

Fangjia Lu

series ordinal

1

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language of work or name

English

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publication date

14 June 2013

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3 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23770306%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

volume

31

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3 March 2020

issue

37

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3 March 2020

page(s)

3979-3986

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Unmet needs in modern vaccinology: adjuvants to improve the immune response

3 March 2020

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Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

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DNA released from dying host cells mediates aluminum adjuvant activity

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Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity

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T-helper 1 and T-helper 2 adjuvants induce distinct differences in the magnitude, quality and kinetics of the early inflammatory response at the site of injection

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Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes

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The adjuvants aluminum hydroxide and MF59 induce monocyte and granulocyte chemoattractants and enhance monocyte differentiation toward dendritic cells

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VACCINE.2013.05.107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23770306%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference