Oral administration of second-generation immunomodulatory oligonucleotides induces mucosal Th1 immune responses and adjuvant activity (Q46393876)

21 December 2017

title

Oral administration of second-generation immunomodulatory oligonucleotides induces mucosal Th1 immune responses and adjuvant activity (English)

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21 December 2017

author name string

Daqing Wang

1

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21 December 2017

Ekambar R Kandimalla

2

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21 December 2017

Dong Yu

3

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21 December 2017

Jimmy X Tang

4

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21 December 2017

Sudhir Agrawal

5

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21 December 2017

language of work or name

English

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publication date

1 April 2005

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21 December 2017

published in

Vaccine

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21 December 2017

volume

23

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21 December 2017

issue

20

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21 December 2017

page(s)

2614-2622

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21 December 2017

Antitumor activity of synthetic oligonucleotides with sequences from cDNA encoding proteins of Mycobacterium bovis BCG

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Stimulation of in vitro proliferation of murine lymphocytes by synthetic oligodeoxynucleotides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

CpG motifs in bacterial DNA trigger direct B-cell activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Immunostimulatory DNA sequences necessary for effective intradermal gene immunization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

A Toll-like receptor recognizes bacterial DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Bacterial DNA induces murine interferon-gamma production by stimulation of interleukin-12 and tumor necrosis factor-alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Pattern and kinetics of cytokine production following administration of phosphorothioate oligonucleotides in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Immunotherapeutic uses of CpG oligodeoxynucleotides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Effect of different chemically modified oligodeoxynucleotides on immune stimulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Antisense and/or immunostimulatory oligonucleotide therapeutics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Effect of chemical modifications of cytosine and guanine in a CpG-motif of oligonucleotides: structure-immunostimulatory activity relationships

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Site of chemical modifications in CpG containing phosphorothioate oligodeoxynucleotide modulates its immunostimulatory activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Immunostimulatory activity of CpG containing phosphorothioate oligodeoxynucleotide is modulated by modification of a single deoxynucleoside

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Immunostimulatory properties of phosphorothioate CpG DNA containing both 3'-5'- and 2'-5'-internucleotide linkages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Immunostimulatory activity of CpG oligonucleotides containing non-ionic methylphosphonate linkages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Modulation of immunostimulatory activity of CpG oligonucleotides by site-specific deletion of nucleobases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Requirement of nucleobase proximal to CpG dinucleotide for immunostimulatory activity of synthetic CpG DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Design, synthesis, and immunostimulatory properties of CpG DNAs containing alkyl-linker substitutions: role of nucleosides in the flanking sequences

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Accessible 5'-end of CpG-containing phosphorothioate oligodeoxynucleotides is essential for immunostimulatory activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Conjugation of ligands at the 5'-end of CpG DNA affects immunostimulatory activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

'Immunomers'--novel 3'-3'-linked CpG oligodeoxyribonucleotides as potent immunomodulatory agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Potent CpG oligonucleotides containing phosphodiester linkages: in vitro and in vivo immunostimulatory properties.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

CpG penta- and hexadeoxyribonucleotides as potent immunomodulatory agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Human papillomavirus virus-like particles are efficient oral immunogens when coadministered with Escherichia coli heat-labile enterotoxin mutant R192G or CpG DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Oral, intrarectal and intranasal immunizations using CpG and non-CpG oligodeoxynucleotides as adjuvants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

CpG DNA is an effective oral adjuvant to protein antigens in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Oral pretreatment of mice with CpG DNA reduces susceptibility to oral or intraperitoneal challenge with virulent Listeria monocytogenes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Orally administered CpG oligodeoxynucleotide induces production of CXC and CC chemokines in the gastric mucosa and suppresses bacterial colonization in a mouse model of Helicobacter pylori infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Absorption, tissue distribution and in vivo stability in rats of a hybrid antisense oligonucleotide following oral administration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

In VivoMetabolic Profile of a Phosphorothioate Oligodeoxyribonucleotide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Preferential Migration of Activated CD4 + and CD8 + T Cells in Response to MIP-1α and MIP-1β

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

Actions of the chemotactic cytokines MCP-1, MCP-2, MCP-3, RANTES, MIP-1 alpha and MIP-1 beta on human monocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2004.11.028

10.1016/J.VACCINE.2004.11.028

7 January 2021

Identifiers

DOI

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21 December 2017

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21 December 2017