Caspase-2 cleavage of tau reversibly impairs memory (Q46467885)

22 December 2017

title

Caspase-2 cleavage of tau reversibly impairs memory (English)

1 reference

22 December 2017

8

Karen H Ashe

1 reference

22 December 2017

author name string

Xiaohui Zhao

1

1 reference

22 December 2017

Linda A Kotilinek

2

1 reference

22 December 2017

Benjamin Smith

3

1 reference

22 December 2017

Chris Hlynialuk

4

1 reference

22 December 2017

Kathleen Zahs

5

1 reference

22 December 2017

Martin Ramsden

6

1 reference

22 December 2017

James Cleary

7

1 reference

22 December 2017

language of work or name

English

0 references

publication date

10 October 2016

1 reference

22 December 2017

published in

Nature Medicine

1 reference

22 December 2017

volume

22

1 reference

22 December 2017

issue

11

1 reference

22 December 2017

page(s)

1268-1276

1 reference

22 December 2017

https://scigraph.springernature.com/pub.10.1038/nm.4199

exact match

0 references

cites work

Tau pathology and neurodegeneration

1 reference

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

21 January 2018

1 reference

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

21 January 2018

1 reference

Neuronal activity regulates extracellular tau in vivo

21 January 2018

1 reference

Differential regulation of dynein and kinesin motor proteins by tau

21 January 2018

1 reference

Caspase activation precedes and leads to tangles

21 January 2018

1 reference

Structural and functional changes in tau mutant mice neurons are not linked to the presence of NFTs

21 January 2018

1 reference

Pathological tau disrupts ongoing network activity.

21 January 2018

1 reference

Tau suppression in a neurodegenerative mouse model improves memory function

21 January 2018

1 reference

Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L).

21 January 2018

1 reference

Synaptic alterations in the rTg4510 mouse model of tauopathy

21 January 2018

1 reference

MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

21 January 2018

1 reference

Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration

21 January 2018

1 reference

Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines

21 January 2018

1 reference

Tau phosphorylation and tau mislocalization mediate soluble Aβ oligomer-induced AMPA glutamate receptor signaling deficits.

21 January 2018

1 reference

The neuronal microtubule-associated protein tau is a substrate for caspase-3 and an effector of apoptosis

21 January 2018

1 reference

The role of caspase cleavage of tau in Alzheimer disease neuropathology

21 January 2018

1 reference

Defects in regulation of apoptosis in caspase-2-deficient mice

21 January 2018

1 reference

Evidence for silent synapses: implications for the expression of LTP.

21 January 2018

1 reference

Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice

21 January 2018

1 reference

Old, new and emerging functions of caspases

21 January 2018

1 reference

Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme

21 January 2018

1 reference

A nonapoptotic role for CASP2/caspase 2: modulation of autophagy

21 January 2018

1 reference

Caspase-2 protects against oxidative stress in vivo

21 January 2018

1 reference

IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.

21 January 2018

1 reference

Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice.

21 January 2018

1 reference

Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease.

21 January 2018

1 reference

Proteolytic processing of tau.

21 January 2018

1 reference

A caspase cleaved form of tau is preferentially degraded through the autophagy pathway

21 January 2018

1 reference

Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease

21 January 2018

1 reference

Tau pathophysiology in neurodegeneration: a tangled issue

21 January 2018

1 reference

A plasmonic chip for biomarker discovery and diagnosis of type 1 diabetes

21 January 2018

1 reference

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

21 January 2018

1 reference

Effect size of memory deficits in mice with adult-onset P301L tau expression

21 January 2018

1 reference

Extended analysis of path data from mutant mice using the public domain software Wintrack

21 January 2018

1 reference

A specific amyloid-beta protein assembly in the brain impairs memory

21 January 2018

1 reference

Noncanonical EF-hand motif strategically delays Ca2+ buffering to enhance cardiac performance

21 January 2018

1 reference

Clinical and pathological correlates of apolipoprotein E ?4 in Alzheimer's disease

21 January 2018

1 reference

Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease.

21 January 2018

1 reference

12 December 2020

C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease.

1 reference

12 December 2020

The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.

1 reference

12 December 2020

Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome.

1 reference

12 December 2020

Characterization and use of monoclonal antibodies to tau and paired helical filament tau.

1 reference

12 December 2020

Caspase-mediated truncation of tau potentiates aggregation

1 reference

12 December 2020

Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.4199

1 reference

22 December 2017

PubMed ID

27723722

1 reference

22 December 2017