MDMA (ecstasy) pharmacokinetics in a CYP2D6 poor metaboliser and in nine CYP2D6 extensive metabolisers. (Q46616769)

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MDMA

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title

MDMA (ecstasy) pharmacokinetics in a CYP2D6 poor metaboliser and in nine CYP2D6 extensive metabolisers (English)

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9

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Rafael de la Torre

1

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2

Magí Farré

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5

Neus Pizarro

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4

Pere N Roset

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6

Mireia Segura

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10

Jordi Camí

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author name string

Brian O Mathúna

3

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Marta Torrens

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Jordi Ortuño

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language of work or name

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23 July 2005

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European Journal of Clinical Pharmacology

4 January 2020

published in

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volume

61

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issue

7

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page(s)

551-554

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https://scigraph.springernature.com/pub.10.1007/s00228-005-0965-y

4 January 2020

exact match

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cites work

The hyperthermic and neurotoxic effects of ‘Ecstasy’ (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype

1 reference

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Determination of MDMA and its metabolites in blood and urine by gas chromatography-mass spectrometry and analysis of enantiomers by capillary electrophoresis

21 January 2018

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Neuroendocrine abnormalities in recreational ecstasy (MDMA) users: is it ecstasy or cannabis?

21 January 2018

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12 December 2020

Cardiovascular and neuroendocrine effects and pharmacokinetics of 3, 4-methylenedioxymethamphetamine in humans

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Serotonergic neurotoxic metabolites of ecstasy identified in rat brain.

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12 December 2020

Repeated doses administration of MDMA in humans: pharmacological effects and pharmacokinetics.

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12 December 2020

The effect of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and its metabolites on neurohypophysial hormone release from the isolated rat hypothalamus

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Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology

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12 December 2020

Polymorphic dextromethorphan metabolism: co-segregation of oxidative O-demethylation with debrisoquin hydroxylation

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3,4-Dihydroxymethamphetamine (HHMA). A major in vivo 3,4-methylenedioxymethamphetamine (MDMA) metabolite in humans

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Multiple toxicity from 3,4-methylenedioxymethamphetamine ("ecstasy").

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12 December 2020

Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences

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Serotonin transporter promoter polymorphism is associated with attenuated prolactin response to fenfluramine

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Altered prolactin response to M-chlorophenylpiperazine in monkeys previously treated with 3,4-methylenedioxymethamphetamine (MDMA) or fenfluramine

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12 December 2020

Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition

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Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease

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