The non-gastric H,K-ATPase as a tool to study the ouabain-binding site in Na,K-ATPase. (Q46715686)

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3 January 2020

title

The non-gastric H,K-ATPase as a tool to study the ouabain-binding site in Na,K-ATPase (English)

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3 January 2020

5

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3 January 2020

author name string

Jan Joep H H M De Pont

1

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3 January 2020

Herman G P Swarts

2

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3 January 2020

Anna Karawajczyk

3

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3 January 2020

Gijs Schaftenaar

4

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3 January 2020

Jan B Koenderink

6

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publication date

7 March 2008

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3 January 2020

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3 January 2020

volume

457

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issue

3

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3 January 2020

page(s)

623-634

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Making optimal use of empirical energy functions: force-field parameterization in crystal space

3 January 2020

cites work

1 reference

12 December 2020

Structure-function studies of Na,K-ATPase. Site-directed mutagenesis of the border residues from the H1-H2 extracellular domain of the alpha subunit.

1 reference

12 December 2020

Lumenal gating mechanism revealed in calcium pump crystal structures with phosphate analogues

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12 December 2020

The non-gastric H,K-ATPase is oligomycin-sensitive and can function as an H+,NH4(+)-ATPase

1 reference

12 December 2020

The human non-gastric H,K-ATPase has a different cation specificity than the rat enzyme.

1 reference

12 December 2020

The alpha-subunit of the colonic H+,K+-ATPase assembles with beta1-Na+,K+-ATPase in kidney and distal colon

1 reference

12 December 2020

Analysis of the gastric H,K ATPase for ion pathways and inhibitor binding sites

1 reference

12 December 2020

Does the colonic H,K-ATPase also act as an Na,K-ATPase?

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12 December 2020

High-affinity ouabain binding by a chimeric gastric H+,K+-ATPase containing transmembrane hairpins M3-M4 and M5-M6 of the alpha 1-subunit of rat Na+,K+-ATPase

1 reference

12 December 2020

Structure-function relationships in the Na,K-ATPase alpha subunit: site-directed mutagenesis of glutamine-111 to arginine and asparagine-122 to aspartic acid generates a ouabain-resistant enzyme

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12 December 2020

Determination of total protein

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12 December 2020

Reconstruction of the complete ouabain-binding pocket of Na,K-ATPase in gastric H,K-ATPase by substitution of only seven amino acids

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12 December 2020

The beta-subunits of Na+,K+-ATPase and gastric H+,K+-ATPase have a high preference for their own alpha-subunit and affect the K+ affinity of these enzymes

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12 December 2020

Fast empirical pKa prediction by Ewald summation.

1 reference

12 December 2020

Evaluation of the FLEXX incremental construction algorithm for protein-ligand docking

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12 December 2020

Loss of acidification of anterior prostate fluids in Atp12a-null mutant mice indicates that nongastric H-K-ATPase functions as proton pump in vivo

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12 December 2020

Sodium acts as a potassium analog on gastric H,K-ATPase

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12 December 2020

Ethanol stimulates expression of functional H+,K(+)-ATPase in SF9 cells

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12 December 2020

The Na(+)-K(+)-ATPase beta 1 subunit is associated with the HK alpha 2 protein in the rat kidney

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12 December 2020

Phe783, Thr797, and Asp804 in transmembrane hairpin M5-M6 of Na+,K+-ATPase play a key role in ouabain binding.

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12 December 2020

Evolution of substrate specificities in the P-type ATPase superfamily.

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12 December 2020

Conversion of the low affinity ouabain-binding site of non-gastric H,K-ATPase into a high affinity binding site by substitution of only five amino acids.

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12 December 2020

Elucidation of the Na+, K+-ATPase digitalis binding site

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12 December 2020

ATP1AL1, a member of the non-gastric H,K-ATPase family, functions as a sodium pump.

1 reference

12 December 2020

The Cambridge Structural Database: a quarter of a million crystal structures and rising

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12 December 2020

Role of homologous ASP334 and GLU319 in human non-gastric H,K- and Na,K-ATPases in cardiac glycoside binding

1 reference

12 December 2020

Structural insights into the binding of cardiac glycosides to the digitalis receptor revealed by solid-state NMR

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12 December 2020

Interactions between cardiac glycosides and sodium/potassium-ATPase: three-dimensional structure-activity relationship models for ligand binding to the E2-Pi form of the enzyme versus activity inhibition.

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12 December 2020

Errors in protein structures

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12 December 2020

Functional expression of gastric H,K-ATPase using the baculovirus expression system

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12 December 2020