Human topoisomerase IIalpha rapidly relaxes positively supercoiled DNA: implications for enzyme action ahead of replication forks (Q46724322)

24 December 2017

title

Human topoisomerase IIalpha rapidly relaxes positively supercoiled DNA: implications for enzyme action ahead of replication forks (English)

1 reference

24 December 2017

author name string

A Kathleen McClendon

series ordinal

1

1 reference

24 December 2017

A Chapin Rodriguez

series ordinal

2

1 reference

24 December 2017

Neil Osheroff

series ordinal

3

1 reference

24 December 2017

language of work or name

English

0 references

publication date

27 September 2005

1 reference

24 December 2017

Journal of Biological Chemistry

published in

1 reference

24 December 2017

volume

280

1 reference

24 December 2017

issue

47

1 reference

24 December 2017

page(s)

39337-39345

1 reference

24 December 2017

Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

A topological view of the replicon

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Cellular roles of dna topoisomerases: a molecular perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Function of DNA topoisomerases as replication swivels in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

The structure of supercoiled intermediates in DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Investigating the biological functions of DNA topoisomerases in eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

DNA topoisomerases: structure, function, and mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Topoisomerase II as a target for anticancer drugs: when enzymes stop being nice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Type IA DNA topoisomerases: strictly one step at a time

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Moving one DNA double helix through another by a type II DNA topoisomerase: the story of a simple molecular machine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Functional expression of a Drosophila gene in yeast: genetic complementation of DNA topoisomerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Yeast DNA topoisomerase II is encoded by a single-copy, essential gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

DNA gyrase and topoisomerase IV: biochemical activities, physiological roles during chromosome replication, and drug sensitivities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Contrasting enzymatic activities of topoisomerase IV and DNA gyrase from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Eukaryotic DNA topoisomerase II beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Topoisomerase II: A specific marker for cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Topoisomerase IV is a target of quinolones in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Fluoroquinolone antibacterials: SAR mechanism of action, resistance, and clinical aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

DNA gyrase as a drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Bacterial topoisomerases, anti-topoisomerases, and anti-topoisomerase resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Etoposide: four decades of development of a topoisomerase II inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Clinical applications of the camptothecins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Tumor cell death induced by topoisomerase-targeting drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

An activity from mammalian cells that untwists superhelical DNA--a possible swivel for DNA replication (polyoma-ethidium bromide-mouse-embryo cells-dye binding assay).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Disruption of a topoisomerase-DNA cleavage complex by a DNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Analysis of topoisomerase function in bacterial replication fork movement: use of DNA microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Preferential relaxation of positively supercoiled DNA by E. coli topoisomerase IV in single-molecule and ensemble measurements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Chirality sensing by Escherichia coli topoisomerase IV and the mechanism of type II topoisomerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Studies of a positive supercoiling machine. Nucleotide hydrolysis and a multifunctional "latch" in the mechanism of reverse gyrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

A unique type II topoisomerase mutant that is hypersensitive to a broad range of cleavage-inducing antitumor agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Cobalt enhances DNA cleavage mediated by human topoisomerase II alpha in vitro and in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

DNA topoisomerases as targets for the anticancer drug TAS-103: DNA interactions and topoisomerase catalytic inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Varying levels of positive and negative supercoiling differently affect the efficiency with which topoisomerase II catenates and decatenates DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Single-molecule study of DNA unlinking by eukaryotic and prokaryotic type-II topoisomerases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Crystal structure of reverse gyrase: insights into the positive supercoiling of DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Transcription-driven twin supercoiling of a DNA loop: a Brownian dynamics study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Kinetic analysis of human topoisomerase IIalpha and beta DNA binding by surface plasmon resonance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Apurinic sites are position-specific topoisomerase II poisons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Human topoisomerase IIalpha possesses an intrinsic nucleic acid specificity for DNA ligation. Use of 5' covalently activated oligonucleotide substrates to study enzyme mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Exocyclic DNA lesions stimulate DNA cleavage mediated by human topoisomerase II alpha in vitro and in cultured cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Hindering the strand passage reaction of human topoisomerase IIalpha without disturbing DNA cleavage, ATP hydrolysis, or the operation of the N-terminal clamp

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Stability of the topoisomerase II closed clamp conformation may influence DNA-stimulated ATP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Structure and mechanism of DNA topoisomerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

DNA strand cleavage is required for replication fork arrest by a frozen topoisomerase-quinolone-DNA ternary complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Mutagenic properties of topoisomerase-targeted drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Endonuclease cleavage of blocked replication forks: An indirect pathway of DNA damage from antitumor drug–topoisomerase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Calcium-promoted DNA cleavage by eukaryotic topoisomerase II: trapping the covalent enzyme-DNA complex in an active form.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

The C-terminal domain of DNA gyrase A adopts a DNA-bending beta-pinwheel fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Crystallization and preliminary X-ray crystallographic analysis of the C-terminal domain of ParC protein from Bacillus stearothermophilus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

The structural basis for substrate specificity in DNA topoisomerase IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Cell death induced by topoisomerase-targeted drugs: more questions than answers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Need for DNA topoisomerase activity as a swivel for DNA replication for transcription of ribosomal RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Reverse gyrase—a topoisomerase which introduces positive superhelical turns into DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503320200

Genetical Implications of the Structure of Deoxyribonucleic Acid

21 January 2018

1 reference

4 November 2023

https://opencitations.net/index/coci/api/v1/citations/10.1038/171964B0

Identifiers

DOI

10.1074/JBC.M503320200

1 reference

24 December 2017

PubMed ID

16188892

1 reference

24 December 2017