Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice. (Q46737694)

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7 January 2020

title

Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice (English)

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7 January 2020

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1

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Murray Barclay

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8

Florkowski CM

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George PM

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author name string

Roberts RL

3

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Harraway J

4

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Zhang M

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Pike LS

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publication date

1 October 2005

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Internal Medicine Journal

7 January 2020

published in

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volume

35

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issue

10

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page(s)

580-585

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The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review

7 January 2020

cites work

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Long-term follow-up of patients with Crohn's disease treated with azathioprine or 6-mercaptopurine.

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The clinical pharmacology of 6-mercaptopurine

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Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease

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6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity

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Nobel Lecture. The purine path to chemotherapy

21 January 2018

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Thiopurine S-methyltransferase (TPMT) genotype does not predict adverse drug reactions to thiopurine drugs in patients with inflammatory bowel disease.

21 January 2018

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Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties

21 January 2018

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A multiplexed allele-specific polymerase chain reaction assay for the detection of common thiopurine S-methyltransferase (TPMT) mutations

21 January 2018

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Thiopurine methyltransferase genotype distribution in patients with Crohn's disease.

21 January 2018

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Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine

21 January 2018

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Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease

21 January 2018

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Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: implications for therapy

21 January 2018

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Monitoring of long-term thiopurine therapy among adults with inflammatory bowel disease

21 January 2018

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The utility of 6-thioguanine metabolite levels in managing patients with inflammatory bowel disease

21 January 2018

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Clinical significance of azathioprine active metabolite concentrations in inflammatory bowel disease

21 January 2018

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Thioguanine-nucleotides do not predict efficacy of tioguanine in Crohn's disease

21 January 2018

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Erythrocyte mean corpuscular volume as a surrogate marker for 6-thioguanine nucleotide concentration monitoring in patients with inflammatory bowel disease treated with azathioprine or 6-mercaptopurine

21 January 2018

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6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease.

21 January 2018

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21 January 2018

Identifiers

DOI

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7 January 2020

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