TERT promotes cellular and organismal survival independently of telomerase activity (Q46788573)

25 December 2017

title

TERT promotes cellular and organismal survival independently of telomerase activity (English)

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25 December 2017

7

W C Hahn

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25 December 2017

author name string

J Lee

1

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25 December 2017

Y H Sung

2

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25 December 2017

C Cheong

3

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25 December 2017

Y S Choi

4

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25 December 2017

H K Jeon

5

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25 December 2017

W Sun

6

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25 December 2017

F Ishikawa

8

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25 December 2017

H-W Lee

9

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25 December 2017

language of work or name

English

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publication date

28 January 2008

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25 December 2017

published in

Oncogene

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25 December 2017

volume

27

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25 December 2017

issue

26

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25 December 2017

page(s)

3754-3760

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25 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1211037

exact match

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cites work

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Reconstitution of human telomerase activity in vitro

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Switching and signaling at the telomere

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Functional characterization and developmental regulation of mouse telomerase RNA.

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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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Template boundary definition in mammalian telomerase

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Extratelomeric functions of telomerase.

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Cellular senescence in cancer and aging

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Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

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BAX is required for neuronal death after trophic factor deprivation and during development

21 January 2018

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X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

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Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death.

21 January 2018

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Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice

21 January 2018

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The common biology of cancer and ageing

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Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells.

21 January 2018

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Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation

21 January 2018

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Inhibition of telomerase limits the growth of human cancer cells.

21 January 2018

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Ectopic expression of the catalytic subunit of telomerase protects against brain injury resulting from ischemia and NMDA-induced neurotoxicity.

21 January 2018

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Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

21 January 2018

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Caspases 3 and 7: key mediators of mitochondrial events of apoptosis

21 January 2018

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Essential role of mouse telomerase in highly proliferative organs

21 January 2018

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Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis

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hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway.

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Telomeres and their control

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Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain

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Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

21 January 2018

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Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria

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Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

21 January 2018

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Brain-derived neurotrophic factor prevents changes in Bcl-2 family members and caspase-3 activation induced by excitotoxicity in the striatum.

21 January 2018

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hTERT antagonizes p53-induced apoptosis independently of telomerase activity.

21 January 2018

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Conditional telomerase induction causes proliferation of hair follicle stem cells

21 January 2018

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Calcium-independent phospholipase A2 localizes in and protects mitochondria during apoptotic induction by staurosporine

21 January 2018

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Telomerase and cancer

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Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres

21 January 2018

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Comparative effects of felbamate and other compounds on N-methyl-D-aspartic acid-induced convulsions and lethality in mice

21 January 2018

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A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

21 January 2018

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

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Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1211037

An alternate splicing variant of the human telomerase catalytic subunit inhibits telomerase activity

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1211037

Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211037

7 January 2021

TERT regulates cell survival independent of telomerase enzymatic activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211037

7 January 2021

p53 and Bax implication in NMDA induced-apoptosis in mouse hippocampus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211037

7 January 2021

Neuromuscular development after the prevention of naturally occurring neuronal death by Bax deletion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211037

7 January 2021

Immunodetection of human telomerase reverse-transcriptase (hTERT) re-appraised: nucleolin and telomerase cross paths

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211037

7 January 2021

Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211037

7 January 2021

TERT suppresses apoptotis at a premitochondrial step by a mechanism requiring reverse transcriptase activity and 14-3-3 protein-binding ability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1211037

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1211037

1 reference

25 December 2017

1 reference

25 December 2017