Protein kinase C negatively regulates Akt activity and modifies UVC-induced apoptosis in mouse keratinocytes (Q46843527)

25 December 2017

title

Protein kinase C negatively regulates Akt activity and modifies UVC-induced apoptosis in mouse keratinocytes (English)

1 reference

25 December 2017

0 references

1 reference

5

Stuart H Yuspa

1 reference

25 December 2017

author name string

Luowei Li

1

1 reference

25 December 2017

Keeran Sampat

2

1 reference

25 December 2017

Nancy Hu

3

1 reference

25 December 2017

Julia Zakari

4

1 reference

25 December 2017

language of work or name

English

0 references

publication date

7 December 2005

1 reference

25 December 2017

Journal of Biological Chemistry

published in

1 reference

25 December 2017

volume

281

1 reference

25 December 2017

page(s)

3237-3243

1 reference

25 December 2017

issue

6

1 reference

25 December 2017

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Role of translocation in the activation and function of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Phosphorylation of Akt/PKB is required for suppression of cancer cell apoptosis and tumor progression in human colorectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

AKT plays a central role in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

PTEN: life as a tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Protean PTEN: form and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Functional roles of Akt signaling in mouse skin tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

In vitro studies on the mode of action of the phorbol esters, potent tumor promoters: part 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Induction of differentiation in normal human keratinocytes by adenovirus-mediated introduction of the eta and delta isoforms of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Differentiation-associated localization of nPKC eta, a Ca(++)-independent protein kinase C, in normal human skin and skin diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Coordinate changes in gene expression which mark the spinous to granular cell transition in epidermis are regulated by protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Relation of the induction of epidermal ornithine decarboxylase and hyperplasia to the different skin tumor-promotion susceptibilities of protein kinase C alpha, -delta and -epsilon transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Insulin-like effects of epidermal growth factor and insulin-like growth factor-I on [3H]2-deoxyglucose uptake, diacylglycerol generation and protein kinase C activation in BC3H-1 myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Selective nuclear translocation of protein kinase C alpha in Swiss 3T3 cells treated with IGF-I, PDGF and EGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Control of cell survival by IGF signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Differential effects of suramin on protein kinase C isoenzymes. A novel tool for discriminating protein kinase C activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

N-protein kinase C isoenzymes may be involved in the regulation of various neutrophil functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Rottlerin, a novel protein kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Knockout of PKC alpha enhances insulin signaling through PI3K

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Negative regulation of phosphatidylinositol 3-kinase and Akt signalling pathway by PKC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Inhibition of insulin-induced activation of Akt by a kinase-deficient mutant of the epsilon isozyme of protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Vascular endothelial growth factor induces protein kinase C (PKC)-dependent Akt/PKB activation and phosphatidylinositol 3'-kinase-mediates PKC delta phosphorylation: role of PKC in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Translocation of protein kinase Cepsilon and protein kinase Cdelta to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinases and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

UV induces phosphorylation of protein kinase B (Akt) at Ser-473 and Thr-308 in mouse epidermal C1 41 cells through hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Phosphatidylinositol-3 kinase is necessary for 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation and activated protein 1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Regulation of protein kinase cascades by protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

N-Ethylmaleimide inhibits platelet-derived growth factor BB-stimulated Akt phosphorylation via activation of protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Stress and radiation-induced activation of multiple intracellular signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Interactions between mitogenic stimuli, or, a thousand and one connections

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Fibroblast growth factors, their receptors and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

Inhibition of protein kinase B/Akt. implications for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512167200

21 January 2018

Identifiers

DOI

10.1074/JBC.M512167200

1 reference

25 December 2017

PubMed ID

16338928

1 reference

25 December 2017