Cartilage degeneration and excessive subchondral bone formation in spontaneous osteoarthritis involves altered TGF-β signaling (Q46848020)

25 December 2017

http://europepmc.org/abstract/MED/26496668

title

Cartilage degeneration and excessive subchondral bone formation in spontaneous osteoarthritis involves altered TGF-β signaling (English)

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25 December 2017

http://europepmc.org/abstract/MED/26496668

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5

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5 June 2020

Chunyi Wen

6

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Kwong Yuen Chiu

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author name string

Weiwei Zhao

1

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Ting Wang

2

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5 June 2020

Qiang Luo

3

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Yan Chen

4

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Mohammed F Shah

7

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Haobo Pan

8

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Xu Cao

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William W Lu

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publication date

23 October 2015

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25 December 2017

http://europepmc.org/abstract/MED/26496668

published in

Journal of Orthopaedic Research

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5 June 2020

volume

34

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issue

5

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page(s)

763-770

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Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

5 June 2020

cites work

1 reference

Diagnosis and treatment of osteoarthritis

21 January 2018

1 reference

The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis

21 January 2018

1 reference

The association of meniscal pathologic changes with cartilage loss in symptomatic knee osteoarthritis

21 January 2018

1 reference

Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis

21 January 2018

1 reference

The electron microscope appearance of the subchondral bone plate in the human femoral head in osteoarthritis and osteoporosis

21 January 2018

1 reference

In vivo structural analysis of subchondral trabecular bone in osteoarthritis of the hip using multi-detector row CT.

21 January 2018

1 reference

Animal models in OA: a means to explore bone.

21 January 2018

1 reference

Fundamental subchondral bone changes in spontaneous knee osteoarthritis

21 January 2018

1 reference

Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity

21 January 2018

1 reference

Transforming growth factor-beta1 to the bone

21 January 2018

1 reference

Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice

21 January 2018

1 reference

TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation

21 January 2018

1 reference

Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis

21 January 2018

1 reference

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the guinea pig

21 January 2018

1 reference

A role for subchondral bone changes in the process of osteoarthritis; a micro-CT study of two canine models.

21 January 2018

1 reference

The role of bone in osteoarthritis pathogenesis

21 January 2018

1 reference

TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage

21 January 2018

1 reference

Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia

21 January 2018

1 reference

Smad transcription factors

21 January 2018

1 reference

Regulation of TGF-beta family signaling by E3 ubiquitin ligases

21 January 2018

1 reference

Loss of Smad3-mediated negative regulation of Runx2 activity leads to an alteration in cell fate determination

21 January 2018

1 reference

Skeletal remodeling in health and disease

21 January 2018

1 reference

Transforming growth factor-beta1 regulates macrophage migration via RhoA.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JOR.23079

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26496668%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

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