Androgen receptor activity is inhibited in response to genotoxic agents in a p53-independent manner (Q46910421)

26 December 2017

title

Androgen receptor activity is inhibited in response to genotoxic agents in a p53-independent manner (English)

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26 December 2017

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Mantoni TS

1

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26 December 2017

Reid G

series ordinal

2

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26 December 2017

Garrett MD

series ordinal

3

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26 December 2017

language of work or name

English

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publication date

1 May 2006

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26 December 2017

published in

Oncogene

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26 December 2017

volume

25

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26 December 2017

issue

22

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26 December 2017

page(s)

3139-3149

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26 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209347

exact match

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cites work

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Transient, ligand-dependent arrest of the androgen receptor in subnuclear foci alters phosphorylation and coactivator interactions

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Molecular determinants of resistance to antiandrogen therapy

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An androgen response element in a far upstream enhancer region is essential for high, androgen-regulated activity of the prostate-specific antigen promoter

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Caspases: the executioners of apoptosis

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Inhibition of p53 function diminishes androgen receptor-mediated signaling in prostate cancer cell lines

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Development of prostate cancer treatment: the good news

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Hsp90 Regulates Androgen Receptor Hormone Binding Affinityin Vivo

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The development of androgen-independent prostate cancer

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Mechanism of antiandrogen action: key role of hsp90 in conformational change and transcriptional activity of the androgen receptor

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Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites

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DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells

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Complete regression of bone metastases on super bone scan, by low-dose cisplatin, UFT, diethylstilbestrol diphosphate, and dexamethasone in a patient with hormone-refractory prostate cancer

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Coregulator recruitment and histone modifications in transcriptional regulation by the androgen receptor.

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Involvement of proteasome in the dynamic assembly of the androgen receptor transcription complex.

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Cell-cycle checkpoints and cancer

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p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways.

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Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

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Is the Achilles' heel for prostate cancer therapy a gain of function in androgen receptor signaling?

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Loss of androgen receptor transcriptional activity at the G(1)/S transition

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The p53 response to DNA damage

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The program of androgen-responsive genes in neoplastic prostate epithelium

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The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

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Radical radiotherapy for prostate cancer

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Hormone resistance in prostate cancer

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7 January 2021

Characterization of two cis-acting DNA elements involved in the androgen regulation of the probasin gene

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The promoter of the prostate-specific antigen gene contains a functional androgen responsive element

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Coregulator codes of transcriptional regulation by nuclear receptors

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7 January 2021

The heat shock protein 90-targeting drug cisplatin selectively inhibits steroid receptor activation

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7 January 2021

Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone

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7 January 2021

p53 represses androgen-induced transactivation of prostate-specific antigen by disrupting hAR amino- to carboxyl-terminal interaction.

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Cytotoxic treatment of aggressive prostate tumors with or without neuroendocrine elements

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Dynamics of intracellular movement and nucleocytoplasmic recycling of the ligand-activated androgen receptor in living cells

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7 January 2021

Phase II trial of estramustine and etoposide in androgen-sensitive metastatic prostate carcinoma

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7 January 2021

A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens

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7 January 2021

HSP90 and the chaperoning of cancer

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7 January 2021

Phosphorylation of androgen receptor isoforms

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7 January 2021

ATM, ATR and DNA-PK: initiators of the cellular genotoxic stress responses.

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209347

1 reference

26 December 2017

1 reference

26 December 2017