Metformin promotes isolated rat liver mitochondria impairment. (Q46971446)

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8 January 2020

title

Metformin promotes isolated rat liver mitochondria impairment (English)

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8 January 2020

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8 January 2020

Sónia C. Correia

2

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8 January 2020

Catarina R. Oliveira

5

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8 January 2020

Paula I. Moreira

6

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8 January 2020

Maria Sancha Santos

3

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8 January 2020

Raquel Seiça

4

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8 January 2020

author name string

Maria S Santos

3

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http://europepmc.org/abstract/MED/17909944

27 December 2017

publication date

2 October 2007

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Molecular and Cellular Biochemistry

8 January 2020

published in

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8 January 2020

volume

308

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8 January 2020

issue

1-2

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8 January 2020

page(s)

75-83

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https://scigraph.springernature.com/pub.10.1007/s11010-007-9614-3

8 January 2020

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Metformin prevents high-glucose-induced endothelial cell death through a mitochondrial permeability transition-dependent process

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Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

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The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

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Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions?

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Possible metformin-induced hepatotoxicity

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Generation of reactive oxygen species by endothelial and smooth muscle cells: influence of hyperglycemia and metformin

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An intracellular modulation of free radical production could contribute to the beneficial effects of metformin towards oxidative stress

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Regulation of the permeability transition pore in skeletal muscle mitochondria. Modulation By electron flow through the respiratory chain complex i.

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Protective effect of melatonin against mitochondrial dysfunction associated with cardiac ischemia- reperfusion: role of cardiolipin.

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Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state

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Liver cell necrosis: cellular mechanisms and clinical implications

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Dual antiglioma action of metformin: cell cycle arrest and mitochondria-dependent apoptosis.

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12 December 2020

Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane

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12 December 2020

The thiol-specific antioxidant enzyme prevents mitochondrial permeability transition. Evidence for the participation of reactive oxygen species in this mechanism

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12 December 2020

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

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12 December 2020

Metformin decreases intracellular production of reactive oxygen species in aortic endothelial cells

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12 December 2020

Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study

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12 December 2020

Mitochondrial bioenergetics as affected by DDT.

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12 December 2020

Mitochondrial permeability transition and oxidative stress

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12 December 2020

Metformin reduces blood pressure and restores endothelial function in aorta of streptozotocin-induced diabetic rats.

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Biguanides. A review of history, pharmacodynamics and therapy

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12 December 2020

Brain and liver mitochondria isolated from diabetic Goto-Kakizaki rats show different susceptibility to induced oxidative stress.

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12 December 2020

Obligatory role of membrane events in the regulatory effect of metformin on the respiratory chain function

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12 December 2020

Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis.

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12 December 2020

Selective electrode for dibenzyl dimethyl amoonium cation as indicator of the membrane potential in biological systems

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Mechanisms of cytochrome c release by proapoptotic BCL-2 family members

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12 December 2020

Modulation of the mitochondrial permeability transition pore. Effect of protons and divalent cations

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12 December 2020

Energy-dependent variation of thiol groups reactivity or accessibility in rat liver mitochondria, revealed by measurements of labelled thiol reagents incorporation

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