C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation (Q47068888)

4 January 2018

title

C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation (English)

1 reference

4 January 2018

Kinase suppressor of Ras B CELE_F58D5.4

main subject

Caenorhabditis elegans

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Kinase suppressor of Ras A CELE_F13B9.5

GOA release 2020-03-11

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GOA release 2020-03-11

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6

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4 January 2018

Tim Schedl

5

object named as

Tim Schedl

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4 January 2018

author name string

Mitsue Ohmachi

1

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4 January 2018

Christian E Rocheleau

2

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4 January 2018

Diane Church

3

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4 January 2018

Eric Lambie

4

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4 January 2018

language of work or name

English

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publication date

1 March 2002

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4 January 2018

published in

Current Biology

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4 January 2018

volume

12

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4 January 2018

page(s)

427-433

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4 January 2018

issue

5

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4 January 2018

The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans

cites work

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7 January 2021

The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction

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7 January 2021

Increasing complexity of the Ras signaling pathway.

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7 January 2021

KSR, a novel protein kinase required for RAS signal transduction

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7 January 2021

A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction

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7 January 2021

Murine Ksr interacts with MEK and inhibits Ras-induced transformation

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7 January 2021

Kinase suppressor of Ras inhibits the activation of extracellular ligand-regulated (ERK) mitogen-activated protein (MAP) kinase by growth factors, activated Ras, and Ras effectors

1 reference

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7 January 2021

KSR stimulates Raf-1 activity in a kinase-independent manner

1 reference

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7 January 2021

C-TAK1 regulates Ras signaling by phosphorylating the MAPK scaffold, KSR1

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7 January 2021

Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization

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7 January 2021

KSR modulates signal propagation within the MAPK cascade

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7 January 2021

Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK.

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7 January 2021

The protein kinase KSR interacts with 14-3-3 protein and Raf.

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7 January 2021

Identification of constitutive and ras-inducible phosphorylation sites of KSR: implications for 14-3-3 binding, mitogen-activated protein kinase binding, and KSR overexpression

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7 January 2021

The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation

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7 January 2021

Kinase suppressor of Ras is ceramide-activated protein kinase

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7 January 2021

Ras is required for a limited number of cell fates and not for general proliferation in Caenorhabditis elegans

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7 January 2021

Genetics of RAS signaling in C. elegans.

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7 January 2021

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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7 January 2021

A sperm cytoskeletal protein that signals oocyte meiotic maturation and ovulation

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7 January 2021

The C. elegans E2F- and DP-related proteins are required for embryonic asymmetry and negatively regulate Ras/MAPK signaling.

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7 January 2021

Kinase suppressor of Ras signals through Thr269 of c-Raf-1.

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7 January 2021

Identification of B-KSR1, a novel brain-specific isoform of KSR1 that functions in neuronal signaling

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7 January 2021

A global profile of germline gene expression in C. elegans

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7 January 2021

Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

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7 January 2021

Development of the reproductive system of Caenorhabditis elegans

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7 January 2021

Ultrastructural features of the adult hermaphrodite gonad of Caenorhabditis elegans: relations between the germ line and soma

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7 January 2021

Muscle organization in Caenorhabditis elegans: localization of proteins implicated in thin filament attachment and I-band organization

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7 January 2021

glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans

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7 January 2021

SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans

1 reference

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7 January 2021

Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction

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7 January 2021

The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway.

1 reference

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7 January 2021

The TRA-1 transcription factor binds TRA-2 to regulate sexual fates in Caenorhabditis elegans

1 reference

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7 January 2021

10.1016/S0960-9822(02)00690-5

Identifiers

DOI

1 reference

4 January 2018

PubMed ID

11882296

1 reference

4 January 2018