The Wilms tumor genes wt1a and wt1b control different steps during formation of the zebrafish pronephros. (Q47073608)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17651719%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

title

The Wilms tumor genes wt1a and wt1b control different steps during formation of the zebrafish pronephros (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17651719%20AND%20SRC:MED&resulttype=core&format=json

WT1 transcription factor a

2 January 2020

main subject

Danio rerio

0 references

1 reference

GOA release 2020-03-11

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17651719%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

author name string

Birgit Perner

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17651719%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Frank Bollig

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17651719%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

language of work or name

English

0 references

publication date

3 July 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17651719%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

published in

Developmental Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17651719%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

volume

309

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17651719%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17651719%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

page(s)

87-96

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17651719%20AND%20SRC:MED&resulttype=core&format=json

Generation of a zebrafish P1 artificial chromosome library

2 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Donor splice-site mutations in WT1 are responsible for Frasier syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Identification and comparative expression analysis of a second wt1 gene in zebrafish.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Localization of the Wilm's tumour protein WT1 in avian embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Making a zebrafish kidney: a tale of two tubes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Truncated WT1 mutants alter the subnuclear localization of the wild-type protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

WT1 activates a glomerular-specific enhancer identified from the human nephrin gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Two-color whole-mount in situ hybridization to vertebrate and Drosophila embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Gata4 regulates the formation of multiple organs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

E-cadherin is a WT1 target gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Parallel early development of zebrafish interrenal glands and pronephros: differential control by wt1 and ff1b

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Molecular basis of the functional podocin-nephrin complex: mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Stages of embryonic development of the zebrafish

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Frasier syndrome is caused by defective alternative splicing of WT1 leading to an altered ratio of WT1 +/-KTS splice isoforms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Organization of the pronephric filtration apparatus in zebrafish requires Nephrin, Podocin and the FERM domain protein Mosaic eyes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

WT-1 is required for early kidney development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Nephropathy and defective spermatogenesis in mice transgenic for a single isoform of the Wilms' tumour suppressor protein, WT1-KTS, together with one disrupted Wt1 allele.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Secretory COPII coat component Sec23a is essential for craniofacial chondrocyte maturation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Twenty ways to lose your bladder: common natural mutants in zebrafish and widespread convergence of swim bladder loss among teleost fishes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Antagonism of WT1 activity by protein self-association.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

YAC transgenic analysis reveals Wilms' tumour 1 gene activity in the proliferating coelomic epithelium, developing diaphragm and limb.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

WT1 induces apoptosis through transcriptional regulation of the proapoptotic Bcl-2 family member Bak.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

WT1 regulates the expression of the major glomerular podocyte membrane protein Podocalyxin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Cell biology of the glomerular podocyte

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

The candidate Wilms' tumour gene is involved in genitourinary development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

WT1-mediated transcriptional activation is inhibited by dominant negative mutant proteins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Wilms' tumour: connecting tumorigenesis and organ development in the kidney

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Plasma membrane targeting of podocin through the classical exocytic pathway: effect of NPHS2 mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

I-SceI meganuclease mediates highly efficient transgenesis in fish.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

The Wilms' tumor gene Wt1 is required for normal development of the retina

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

The major podocyte protein nephrin is transcriptionally activated by the Wilms' tumor suppressor WT1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022

Coronary vessel development requires activation of the TrkB neurotrophin receptor by the Wilms' tumor transcription factor Wt1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.022