STING Activation Reverses Lymphoma-Mediated Resistance to Antibody Immunotherapy (Q47122380)

http://europepmc.org/abstract/PMC/5500176

8 January 2018

title

STING Activation Reverses Lymphoma-Mediated Resistance to Antibody Immunotherapy (English)

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http://europepmc.org/abstract/PMC/5500176

8 January 2018

1 reference

1 reference

12

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28512240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jessica L. Teeling

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28512240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Mark S Cragg

15

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28512240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Stephen A Beers

16

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ORCID Public Data File 2021

author name string

Lekh N Dahal

1

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10 June 2020

Lang Dou

2

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10 June 2020

Khiyam Hussain

3

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10 June 2020

Rena Liu

4

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10 June 2020

Alexander Earley

5

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10 June 2020

Kerry L Cox

6

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10 June 2020

Salome Murinello

7

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10 June 2020

Ian Tracy

8

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10 June 2020

Francesco Forconi

9

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10 June 2020

Andrew J Steele

10

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10 June 2020

Patrick J Duriez

11

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10 June 2020

Martin J Glennie

14

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10 June 2020

language of work or name

English

0 references

publication date

16 May 2017

1 reference

http://europepmc.org/abstract/PMC/5500176

8 January 2018

published in

Cancer Research

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28512240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

77

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10 June 2020

issue

13

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10 June 2020

page(s)

3619-3631

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28512240%20AND%20SRC:MED&resulttype=core&format=json

The Role of Regulatory B Cell-Like Malignant Cells and Treg Cells in the Mouse Model of BCL1 Tumor Dormancy

10 June 2020

cites work

1 reference

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Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells

23 May 2018

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New insights into the multidimensional concept of macrophage ontogeny, activation and function.

23 May 2018

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Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors

23 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500176

Development and Characterization of Monoclonal Antibodies Specific for Mouse and Human Fcγ Receptors

23 May 2018

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FcγR requirements leading to successful immunotherapy

23 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500176

Reprogramming of macrophages--new opportunities for therapeutic targeting

23 May 2018

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FcγRs Modulate the Anti-tumor Activity of Antibodies Targeting the PD-1/PD-L1 Axis

23 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500176

Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500176

Antagonistic human FcγRIIB (CD32B) antibodies have anti-tumor activity and overcome resistance to antibody therapy in vivo.

23 May 2018

1 reference

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The STING pathway and the T cell-inflamed tumor microenvironment

23 May 2018

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DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500176

Antigenic modulation limits the effector cell mechanisms employed by type I anti-CD20 monoclonal antibodies

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500176

STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500176

Macrophage heterogeneity in tissues: phenotypic diversity and functions

23 May 2018

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Macrophage activation and polarization: nomenclature and experimental guidelines

23 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500176

DMXAA causes tumor site-specific vascular disruption in murine non-small cell lung cancer, and like the endogenous non-canonical cyclic dinucleotide STING agonist, 2'3'-cGAMP, induces M2 macrophage repolarization

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500176

Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500176

Macrophages eliminate circulating tumor cells after monoclonal antibody therapy

23 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500176

Innate and adaptive immune cells in the tumor microenvironment

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500176

Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid

23 May 2018

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Using macrophage activation to augment immunotherapy of established tumours

23 May 2018

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Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

23 May 2018

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Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

23 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5500176

Lipopolysaccharide induces CD38 expression and solubilization in J774 macrophage cells

23 May 2018

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Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions.

23 May 2018

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Coordinated regulation of myeloid cells by tumours

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23 May 2018

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STING is a direct innate immune sensor of cyclic di-GMP

23 May 2018

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Fc gamma receptor IIb on target B cells promotes rituximab internalization and reduces clinical efficacy.

23 May 2018

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In situ vaccination with a TLR9 agonist induces systemic lymphoma regression: a phase I/II study

23 May 2018

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Alternative activation of macrophages: mechanism and functions

23 May 2018

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Macrophage diversity enhances tumor progression and metastasis

23 May 2018

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Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma

23 May 2018

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23 May 2018

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12 December 2020

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28512240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28512240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference