Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA (Q28118718)

Gene Ontology release 2020-05-02

1 reference

ChEBI release 2020-05-28

ChEBI ID

71580

Cyclic GMP-AMP synthase

1 reference

2',3'-cyclic GMP-AMP synthase activity

GOA release 2020-03-11

1 reference

Transmembrane protein 173

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Jiaxi Wu

1

0 references

Chuo Chen

object named as

Chuo Chen

6

0 references

Zhijian Chen

1 reference

ORCID Public Data File 2021

author name string

Lijun Sun

2

1 reference

4 January 2017

Xiang Chen

3

1 reference

4 January 2017

Fenghe Du

4

1 reference

4 January 2017

Heping Shi

5

1 reference

4 January 2017

Zhijian J. Chen

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

7

1 reference

4 January 2017

language of work or name

English

0 references

publication date

15 February 2013

1 reference

4 January 2017

1 reference

4 January 2017

339

1 reference

4 January 2017

826–830

1 reference

4 January 2017

6121

1 reference

4 January 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

Cyclic di-GMP sensing via the innate immune signaling protein STING

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

STING is a direct innate immune sensor of cyclic di-GMP

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

Cytoplasmic DNA innate immune pathways

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

Coordinated regulation of accessory genetic elements produces cyclic di-nucleotides for V. cholerae virulence

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

20 March 2017

1 reference

Crossref

https://api.crossref.org/works/10.1126/SCIENCE.1229963

The prokaryote messenger c-di-GMP triggers stalk cell differentiation in Dictyostelium.

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

Earl Sutherland (1915-1974) [corrected] and the discovery of cyclic AMP.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

Nucleic acid recognition by the innate immune system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

Bacterial nucleotide-based second messengers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

Herpes simplex virus ICP0 and ICP34.5 counteract distinct interferon-induced barriers to virus replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855410

The specific and essential role of MAVS in antiviral innate immune responses

29 September 2017

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23258412

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1229963

1 reference

release_d7kvf5et5zfkfdxvlhnhzacx7e

320352

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/d7kvf5et5zfkfdxvlhnhzacx7e

mapped directly with Wikidata item

24 November 2022

based on heuristic

320352

1 reference

1 reference

1 reference