Sulforaphane reduces YAP/∆Np63α signaling to reduce cancer stem cell survival and tumor formation (Q47158107)

9 January 2018

title

Sulforaphane reduces YAP/∆Np63α signaling to reduce cancer stem cell survival and tumor formation (English)

1 reference

9 January 2018

main subject

neoplastic stem cells

1 reference

Daniel Grun

3

0 references

author name string

Matthew L Fisher

1

1 reference

9 January 2018

Nicholas Ciavattone

2

1 reference

9 January 2018

Gautam Adhikary

4

1 reference

9 January 2018

Richard L Eckert

5

1 reference

9 January 2018

language of work or name

English

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publication date

27 August 2017

1 reference

9 January 2018

number of pages

12

1 reference

based on heuristic

inferred from page(s)

published in

Oncotarget

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9 January 2018

volume

8

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9 January 2018

issue

43

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9 January 2018

page(s)

73407-73418

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9 January 2018

Transglutaminase Interaction with α6/β4-Integrin Stimulates YAP1-Dependent ΔNp63α Stabilization and Leads to Enhanced Cancer Stem Cell Survival and Tumor Formation.

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VEGF-A acts via neuropilin-1 to enhance epidermal cancer stem cell survival and formation of aggressive and highly vascularized tumors.

23 May 2018

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The Ezh2 polycomb group protein drives an aggressive phenotype in melanoma cancer stem cells and is a target of diet derived sulforaphane.

23 May 2018

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Transglutaminase is a tumor cell and cancer stem cell survival factor

23 May 2018

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23 May 2018

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Survival of skin cancer stem cells requires the Ezh2 polycomb group protein.

23 May 2018

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23 May 2018

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23 May 2018

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Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation

23 May 2018

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23 May 2018

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Kinetics of sulforaphane in mice after consumption of sulforaphane-enriched broccoli sprout preparation

23 May 2018

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Chemoprevention of prostate cancer by d,l-sulforaphane is augmented by pharmacological inhibition of autophagy

23 May 2018

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Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China

23 May 2018

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Sulforaphane suppresses polycomb group protein level via a proteasome-dependent mechanism in skin cancer cells

23 May 2018

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Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells

23 May 2018

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Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin

23 May 2018

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Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells

23 May 2018

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23 May 2018

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Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention

23 May 2018

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Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention

23 May 2018

1 reference

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Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5650271

Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates

23 May 2018

1 reference

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Multi-targeted prevention of cancer by sulforaphane

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5650271

TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5650271

p63 Is essential for the proliferative potential of stem cells in stratified epithelia

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5650271

p63 is the molecular switch for initiation of an epithelial stratification program

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5650271

Sulforaphane induces caspase-mediated apoptosis in cultured PC-3 human prostate cancer cells and retards growth of PC-3 xenografts in vivo

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5650271

Epidermal differentiation: transgenic/knockout mouse models reveal genes involved in stem cell fate decisions and commitment to differentiation

23 May 2018

1 reference

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p63 expression in normal skin and usual cutaneous carcinomas

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5650271

p63 is a p53 homologue required for limb and epidermal morphogenesis

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5650271

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5650271

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5650271

Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5650271

Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5650271

Sulforaphane as a promising molecule for fighting cancer

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5650271

Requirement and epigenetics reprogramming of Nrf2 in suppression of tumor promoter TPA-induced mouse skin cell transformation by sulforaphane

3 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29088716

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.20562

1 reference

9 January 2018

PMC publication ID

5650271

1 reference

9 January 2018

PubMed publication ID

29088716

1 reference

9 January 2018