An enhancer element at the Igf2/H19 locus drives gene expression in both imprinted and non-imprinted tissues. (Q47273848)

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30 December 2019

title

An enhancer element at the Igf2/H19 locus drives gene expression in both imprinted and non-imprinted tissues (English)

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30 December 2019

1

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30 December 2019

Trevelyan R Menheniott

2

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30 December 2019

William Bennett

3

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30 December 2019

Andrew Ward

7

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30 December 2019

author name string

Sharon M Kelly

4

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30 December 2019

Ghislaine Dell

5

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30 December 2019

Luisa Dandolo

6

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30 December 2019

language of work or name

English

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publication date

1 July 2004

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30 December 2019

published in

Developmental Biology

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30 December 2019

volume

271

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30 December 2019

issue

2

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30 December 2019

page(s)

488-497

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Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

30 December 2019

cites work

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Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism

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Deletion of a silencer element in Igf2 results in loss of imprinting independent of H19.

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An upstream repressor element plays a role in Igf2 imprinting

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Epigenotype-phenotype correlations in Beckwith-Wiedemann syndrome

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Polycomb-group proteins are involved in silencing processes caused by a transgenic element from the murine imprinted H19/Igf2 region in Drosophila.

7 January 2021

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Loss of the maternal H19 gene induces changes in Igf2 methylation in both cis and trans

7 January 2021

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CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

7 January 2021

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Comparative genomic sequencing identifies novel tissue-specific enhancers and sequence elements for methylation-sensitive factors implicated in Igf2/H19 imprinting

7 January 2021

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Deletion of a nuclease-sensitive region between the Igf2 and H19 genes leads to Igf2 misregulation and increased adiposity

7 January 2021

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Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive

7 January 2021

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Comparative analysis of Igf-2/H19 imprinted domain: identification of a highly conserved intergenic DNase I hypersensitive region.

7 January 2021

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Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions.

7 January 2021

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Prealbumin gene expression during mouse development studied by in situ hybridization

7 January 2021

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An intragenic methylated region in the imprinted Igf2 gene augments transcription.

7 January 2021

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The nucleotides responsible for the direct physical contact between the chromatin insulator protein CTCF and the H19 imprinting control region manifest parent of origin-specific long-distance insulation and methylation-free domains

7 January 2021

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Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element

7 January 2021

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Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene.

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Expression of the insulin-like growth factor II gene in the choroid plexus and the leptomeninges of the adult rat central nervous system

7 January 2021

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H19 is imprinted in the choroid plexus and leptomeninges of the mouse foetus

7 January 2021

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Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function.

7 January 2021

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Genomic regions regulating imprinting and insulin-like growth factor-II promoter 3 activity in transgenics: novel enhancer and silencer elements.

7 January 2021

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Extensive tissue-specific variation of allelic methylation in the Igf2 gene during mouse fetal development: relation to expression and imprinting

7 January 2021

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