Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing. (Q47355595)

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2 April 2020

title

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing (English)

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2 April 2020

16

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Mehmet Fatih Bolukbasi

8

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Lihua Julie Zhu

9

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Haiwei Mou

11

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Wen Xue

19

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2 April 2020

Robert S. Langer, Jr.

20

object named as

Robert Langer

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2 April 2020

Victor E. Koteliansky

17

object named as

Victor Koteliansky

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21

Daniel G Anderson

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3

Sneha Suresh

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15

Roman L Bogorad

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18

Scot A Wolfe

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10

Kevin Kauffman

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2 April 2020

13

Junmei Ding

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14

Suet-Yan Kwan

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2 April 2020

author name string

Hao Yin

1

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2 April 2020

Chun-Qing Song

2

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2 April 2020

Qiongqiong Wu

4

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2 April 2020

Stephen Walsh

5

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Luke Hyunsik Rhym

6

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Esther Mintzer

7

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Alicia Oberholzer

12

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publication date

13 November 2017

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2 April 2020

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2 April 2020

volume

35

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issue

12

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2 April 2020

page(s)

1179-1187

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GUIDEseq: a bioconductor package to analyze GUIDE-Seq datasets for CRISPR-Cas nucleases.

2 April 2020

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In vivo gene editing in dystrophic mouse muscle and muscle stem cells

16 June 2018

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In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

16 June 2018

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Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy.

16 June 2018

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16 June 2018

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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system

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16 June 2018

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Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells

16 June 2018

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STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

16 June 2018

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Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses.

16 June 2018

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Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis

16 June 2018

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In vivo genome editing using Staphylococcus aureus Cas9

16 June 2018

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Therapeutic genome editing: prospects and challenges

16 June 2018

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Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

16 June 2018

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16 June 2018

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16 June 2018

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16 June 2018

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16 June 2018

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16 June 2018

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16 June 2018

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16 June 2018

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16 June 2018

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16 June 2018

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16 June 2018

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16 June 2018

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16 June 2018

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16 June 2018

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Chemical modification of siRNAs for in vivo use.

16 June 2018

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siRNA function in RNAi: a chemical modification analysis

16 June 2018

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Lactoferrin protects against concanavalin A-induced liver injury in mice

16 June 2018

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2'-O-methyl-modified RNAs act as TLR7 antagonists

14 August 2018

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Crossref

https://api.crossref.org/works/10.1038%2FNBT.4005

inferred from DOI database lookup

7 January 2021

based on heuristic

Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNBT.4005

inferred from DOI database lookup

7 January 2021

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Prostaglandin I(2) and E(2) mediate the protective effects of cyclooxygenase-2 in a mouse model of immune-mediated liver injury

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inferred from DOI database lookup

7 January 2021

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Identifiers

DOI

10.1038/NBT.4005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29131148%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

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2 April 2020

PubMed publication ID

29131148

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