Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion. (Q47406440)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29074774%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

title

Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion (English)

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8 April 2020

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11 September 2018

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10

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Armiyaw S Nasamu

1

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8 April 2020

Svetlana Glushakova

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8 April 2020

Ilaria Russo

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8 April 2020

Arthur S. Kim

6

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8 April 2020

Niraj H Tolia

8

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Jacquin C Niles

11

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8 April 2020

Joshua Zimmerberg

12

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8 April 2020

Daniel E Goldberg

13

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8 April 2020

7

Daved H Fremont

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8 April 2020

author name string

Barbara Vaupel

4

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8 April 2020

Anna Oksman

5

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8 April 2020

Josh R Beck

9

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8 April 2020

language of work or name

English

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publication date

1 October 2017

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8 April 2020

number of pages

5

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based on heuristic

inferred from page(s)

published in

Science

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8 April 2020

volume

358

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issue

6362

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8 April 2020

page(s)

518-522

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Esterase mutation is a mechanism of resistance to antimalarial compounds

8 April 2020

cites work

1 reference

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The chaperonin TRiC forms an oligomeric complex in the malaria parasite cytosol

29 September 2018

1 reference

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Synthetic RNA-protein modules integrated with native translation mechanisms to control gene expression in malaria parasites

29 September 2018

1 reference

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Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Plasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycle

29 September 2018

1 reference

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A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Evaluation of aminohydantoins as a novel class of antimalarial agents.

29 September 2018

1 reference

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Key molecular events during host cell invasion by Apicomplexan pathogens

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Plasmodium falciparum heat shock protein 110 stabilizes the asparagine repeat-rich parasite proteome during malarial fevers

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Recent advances in plasmepsin medicinal chemistry and implications for future antimalarial drug discovery efforts

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Structural studies of vacuolar plasmepsins

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Thousands of chemical starting points for antimalarial lead identification

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Plasmepsin V licenses Plasmodium proteins for export into the host erythrocyte

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

An aspartyl protease directs malaria effector proteins to the host cell

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

The malaria parasite cyclic GMP-dependent protein kinase plays a central role in blood-stage schizogony

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

A multifunctional serine protease primes the malaria parasite for red blood cell invasion

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Critical roles for the digestive vacuole plasmepsins of Plasmodium falciparum in vacuolar function

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Quantification of malaria parasite release from infected erythrocytes: inhibition by protein-free media

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparum

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Inhibitors of the Plasmodium falciparum parasite aspartic protease plasmepsin II as potential antimalarial agents

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Expression of recombinant Plasmodium falciparum subtilisin-like protease-1 in insect cells. Characterization, comparison with the parasite protease, and homology modeling

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

Maturation and specificity of Plasmodium falciparum subtilisin-like protease-1, a malaria merozoite subtilisin-like serine protease

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5928414

29 September 2018

Identifiers

DOI

10.1126/SCIENCE.AAN1478

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29074774%20AND%20SRC:MED&resulttype=core&format=json

release_jmvkmad67bgprc3p3cr47f2ure

8 April 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/jmvkmad67bgprc3p3cr47f2ure

mapped directly with Wikidata item

24 November 2022

based on heuristic

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29074774%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

PubMed publication ID

29074774

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