ESX/type VII secretion systems of mycobacteria: Insights into evolution, pathogenicity and protection (Q47433141)

16 January 2018

title

ESX/type VII secretion systems of mycobacteria: Insights into evolution, pathogenicity and protection (English)

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16 January 2018

Roland Brosch

5

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author name string

Roxane Simeone

1

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16 January 2018

Daria Bottai

2

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16 January 2018

Wafa Frigui

3

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16 January 2018

Laleh Majlessi

4

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16 January 2018

publication date

13 February 2015

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16 January 2018

published in

Tuberculosis

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16 January 2018

volume

95 Suppl 1

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16 January 2018

page(s)

S150-4

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16 January 2018

Non mycobacterial virulence genes in the genome of the emerging pathogen Mycobacterium abscessus

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Identification and characterization of the genetic changes responsible for the characteristic smooth-to-rough morphotype alterations of clinically persistent Mycobacterium abscessus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Massive gene decay in the leprosy bacillus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Pathogenicity in the tubercle bacillus: molecular and evolutionary determinants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Direct visualization of the outer membrane of mycobacteria and corynebacteria in their native state

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Disclosure of the mycobacterial outer membrane: cryo-electron tomography and vitreous sections reveal the lipid bilayer structure.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

SecA2 functions in the secretion of superoxide dismutase A and in the virulence of Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

The twin-arginine translocation pathway of Mycobacterium smegmatis is functional and required for the export of mycobacterial beta-lactamases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Genes required for mycobacterial growth defined by high density mutagenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

The ESAT-6/WXG100 superfamily -- and a new Gram-positive secretion system?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

ESAT-6 proteins: protective antigens and virulence factors?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Type VII secretion--mycobacteria show the way.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

A Mycobacterium tuberculosis operon encoding ESAT-6 and a novel low-molecular-mass culture filtrate protein (CFP-10)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Comparative genomics of BCG vaccines by whole-genome DNA microarray

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

BCG and vole bacillus vaccines in the prevention of tuberculosis in adolescence and early adult life

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Analysis of the proteome of Mycobacterium tuberculosis in silico

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Composition of the type VII secretion system membrane complex.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Characterization of a Mycobacterium tuberculosis ESX-3 conditional mutant: essentiality and rescue by iron and zinc

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Systematic genetic nomenclature for type VII secretion systems.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

The mycosins of Mycobacterium tuberculosis H37Rv: a family of subtilisin-like serine proteases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Mycosin-1, a subtilisin-like serine protease of Mycobacterium tuberculosis, is cell wall-associated and expressed during infection of macrophages.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Mutually dependent secretion of proteins required for mycobacterial virulence.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA-independent virulence.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

MprAB regulates the espA operon in Mycobacterium tuberculosis and modulates ESX-1 function and host cytokine response.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Distributive conjugal transfer in mycobacteria generates progeny with meiotic-like genome-wide mosaicism, allowing mapping of a mating identity locus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

ESX/type VII secretion systems and their role in host-pathogen interaction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Genome plasticity of BCG and impact on vaccine efficacy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Activation of the NLRP3 inflammasome byMycobacterium tuberculosisis uncoupled from susceptibility to active tuberculosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Antigen Load Governs the Differential Priming of CD8 T Cells in Response to the Bacille Calmette Guerin Vaccine or Mycobacterium tuberculosis Infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

PPE and PE_PGRS proteins ofMycobacterium marinumare transported via the type VII secretion system ESX-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

The ESX-5 associated eccB-EccC locus is essential for Mycobacterium tuberculosis viability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

A specific secretion system mediates PPE41 transport in pathogenic mycobacteria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

General secretion signal for the mycobacterial type VII secretion pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Mycobacterial PE, PPE and ESX clusters: novel insights into the secretion of these most unusual protein families

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TUBE.2015.02.019

inferred from DOI database lookup

7 January 2021

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Identifiers

DOI

10.1016/J.TUBE.2015.02.019

1 reference

16 January 2018

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16 January 2018