Impact of combined HDAC and mTOR inhibition on adhesion, migration and invasion of prostate cancer cells (Q47589926)

4 February 2018

title

Impact of combined HDAC and mTOR inhibition on adhesion, migration and invasion of prostate cancer cells (English)

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4 February 2018

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9

Roman A Blaheta

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4 February 2018

author name string

Steffen Wedel

1

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Lukasz Hudak

2

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Jens-Michael Seibel

3

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Jasmina Makarević

4

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Eva Juengel

5

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Igor Tsaur

6

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Christoph Wiesner

7

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Axel Haferkamp

8

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publication date

31 March 2011

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Clinical & Experimental Metastasis

published in

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4 February 2018

volume

28

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issue

5

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page(s)

479-491

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4 February 2018

cites work

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Multiple Molecular pathways explain the anti-proliferative effect of valproic acid on prostate cancer cells in vitro and in vivo

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Chronic administration of valproic acid inhibits prostate cancer cell growth in vitro and in vivo

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RAD001 (Everolimus) inhibits growth of prostate cancer in the bone and the inhibitory effects are increased by combination with docetaxel and zoledronic acid

21 January 2018

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Synergistic effect of a novel antiandrogen, VN/124-1, and signal transduction inhibitors in prostate cancer progression to hormone independence in vitro.

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Type I collagen receptor (alpha 2 beta 1) signaling promotes the growth of human prostate cancer cells within the bone

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Reorganization of the integrin alpha2 subunit controls cell adhesion and cancer cell invasion in prostate cancer

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Histone deacetylases are required for androgen receptor function in hormone-sensitive and castrate-resistant prostate cancer

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Different phenotypes in human prostate cancer: alpha6 or alpha3 integrin in cell-extracellular adhesion sites

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Osteoblasts-derived BMP-2 enhances the motility of prostate cancer cells via activation of integrins.

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Beta3 integrins facilitate matrix interactions during transendothelial migration of PC3 prostate tumor cells

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RGD-containing peptides activate S6K1 through beta3 integrin in adult cardiac muscle cells

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Preferential chemosensitization of PTEN-mutated prostate cells by silencing the Akt kinase

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Combination strategy targeting the hypoxia inducible factor-1 alpha with mammalian target of rapamycin and histone deacetylase inhibitors

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Vorinostat enhances the activity of temsirolimus in renal cell carcinoma through suppression of survivin levels

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LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cells

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Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes

21 January 2018

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Inhibitory effect of HGF on invasiveness of aggressive MDA-MB231 breast carcinoma cells, and role of HDACs.

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Alpha9beta1 integrin in melanoma cells can signal different adhesion states for migration and anchorage

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Dietary genistein inhibits metastasis of human prostate cancer in mice

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Expression of mTOR signaling pathway markers in prostate cancer progression

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12 December 2020

Focal adhesion disassembly requires clathrin-dependent endocytosis of integrins

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12 December 2020

The alpha-receptor for platelet-derived growth factor as a target for antibody-mediated inhibition of skeletal metastases from prostate cancer cells

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12 December 2020

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12 December 2020

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12 December 2020

Inhibitory effect of fucoidan on the adhesion of adenocarcinoma cells to fibronectin

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12 December 2020

Increased expression of histone deacetylaces (HDACs) and inhibition of prostate cancer growth and invasion by HDAC inhibitor SAHA.

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12 December 2020

Determining risk of biochemical recurrence in prostate cancer by immunohistochemical detection of PTEN expression and Akt activation

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10.1007/S10585-011-9386-8

Identifiers

DOI

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4 February 2018

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4 February 2018