Androgenic to oestrogenic switch in the human adult prostate gland is regulated by epigenetic silencing of steroid 5α-reductase 2. (Q47756626)

PubMed publication ID

28940538

5 February 2018

http://europepmc.org/abstract/MED/28940538

title

Androgenic to oestrogenic switch in the human adult prostate gland is regulated by epigenetic silencing of steroid 5α-reductase 2 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

Douglas W. Strand

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

author name string

Libing Hu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

Keyan Salari

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

Seth K Bechis

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

Rongbin Ge

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

Shulin Wu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

Cyrus Rassoulian

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

Jonathan Pham

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

Chin-Lee Wu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

Shahin Tabatabaei

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

Aria F Olumi

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

publication date

20 September 2017

1 reference

PubMed publication ID

28940538

5 February 2018

http://europepmc.org/abstract/MED/28940538

language of work

Journal of Pathology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

volume

243

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

page(s)

457-467

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

Prostate volume changes over time: results from the Baltimore Longitudinal Study of Aging

12 May 2020

cites work

1 reference

Pharmacological therapy of benign prostatic hyperplasia/lower urinary tract symptoms: an overview for the practising clinician

21 January 2018

1 reference

A population based study of incidence and treatment of benign prostatic hyperplasia among residents of Olmsted County, Minnesota: 1987 to 1997.

21 January 2018

1 reference

Steroid 5alpha-reductase deficiency in man: an inherited form of male pseudohermaphroditism

21 January 2018

1 reference

Familial incomplete male pseudohermaphroditism, type 2. Decreased dihydrotestosterone formation in pseudovaginal perineoscrotal hypospadias.

21 January 2018

1 reference

5α-Reductase type 1 deficiency or inhibition predisposes to insulin resistance, hepatic steatosis, and liver fibrosis in rodents.

21 January 2018

1 reference

5α-reductase type 3 expression in human benign and malignant tissues: a comparative analysis during prostate cancer progression

21 January 2018

1 reference

SRD5A3: A surprising role in glycosylation

21 January 2018

1 reference

The effect of finasteride on the risk of acute urinary retention and the need for surgical treatment among men with benign prostatic hyperplasia. Finasteride Long-Term Efficacy and Safety Study Group

21 January 2018

1 reference

Age and Obesity Promote Methylation and Suppression of 5α-Reductase 2: Implications for Personalized Therapy of Benign Prostatic Hyperplasia

21 January 2018

1 reference

Cancer epigenomics: DNA methylomes and histone-modification maps

21 January 2018

1 reference

Personalized medicine for the management of benign prostatic hyperplasia

21 January 2018

1 reference

Estrogen action on the prostate gland: a critical mix of endocrine and paracrine signaling.

21 January 2018

1 reference

Estrogen receptor-α is a key mediator and therapeutic target for bladder complications of benign prostatic hyperplasia

21 January 2018

1 reference

Androgens and estrogens in benign prostatic hyperplasia: past, present and future

21 January 2018

1 reference

Estrogens and Male Lower Urinary Tract Dysfunction

21 January 2018

1 reference

Association between lower urinary tract symptoms and serum levels of sex hormones in men.

21 January 2018

1 reference

Purification and direct transformation of epithelial progenitor cells from primary human prostate

21 January 2018

1 reference

Isolation and analysis of discreet human prostate cellular populations

21 January 2018

1 reference

Non-Cell-Autonomous Regulation of Prostate Epithelial Homeostasis by Androgen Receptor.

21 January 2018

1 reference

21 January 2018

1 reference

Adjusting batch effects in microarray expression data using empirical Bayes methods

21 January 2018

1 reference

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 January 2018

1 reference

Steroid hormones and carcinogenesis of the prostate: the role of estrogens

21 January 2018

1 reference

The dual, opposing roles of estrogen in the prostate.

21 January 2018

1 reference

Stromally expressed c-Jun regulates proliferation of prostate epithelial cells

21 January 2018

1 reference

Aromatase and regulating the estrogen:androgen ratio in the prostate gland.

21 January 2018

1 reference

The endocrinology and developmental biology of the prostate

21 January 2018

1 reference

Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade

21 January 2018

1 reference

Organoid cultures derived from patients with advanced prostate cancer

21 January 2018

1 reference

Copy number alteration burden predicts prostate cancer relapse

21 January 2018

1 reference

Local aromatase expression in human prostate is altered in malignancy

21 January 2018

1 reference

Histological localization of estrogen receptors in normal and diseased human prostates by immunocytochemistry

21 January 2018

1 reference

Sex steroid receptor expression and localization in benign prostatic hyperplasia varies with tissue compartment

21 January 2018

1 reference

Estrogen receptor beta agonist LY500307 fails to improve symptoms in men with enlarged prostate secondary to benign prostatic hypertrophy

21 January 2018

1 reference

Impact of constitutional genetic variation in androgen/oestrogen-regulating genes on age-related changes in human prostate

21 January 2018

1 reference

Estrogen receptors α and β and aromatase as independent predictors for prostate cancer outcome

21 January 2018

1 reference

Cyclin A1 and P450 Aromatase Promote Metastatic Homing and Growth of Stem-like Prostate Cancer Cells in the Bone Marrow.

21 January 2018

1 reference

Prostatic hormonal carcinogenesis is mediated by in situ estrogen production and estrogen receptor alpha signaling.

21 January 2018

1 reference

Effects of Transdermal Testosterone Gel or an Aromatase Inhibitor on Prostate Volume in Older Men

21 January 2018

1 reference

Inflammation and increased aromatase expression occur in the breast tissue of obese women with breast cancer

21 January 2018

1 reference

The influence of finasteride on the development of prostate cancer

21 January 2018

1 reference

Treatment with finasteride preserves usefulness of prostate-specific antigen in the detection of prostate cancer: results of a randomized, double-blind, placebo-controlled clinical trial. PLESS Study Group. Proscar Long-term Efficacy and Safety Stud

21 January 2018

1 reference

Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy

21 January 2018

1 reference

Time Course of Incident Adverse Experiences Associated with Doxazosin, Finasteride and Combination Therapy in Men with Benign Prostatic Hyperplasia: The MTOPS Trial.

21 January 2018

1 reference

DNA methyl transferase 1 reduces expression of SRD5A2 in the aging adult prostate

21 January 2018

1 reference

Inhibition of TNF-α improves the bladder dysfunction that is associated with type 2 diabetes

21 January 2018

1 reference

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

21 January 2018

1 reference

Polymorphisms in genes involved in sex hormone metabolism may increase risk of benign prostatic hyperplasia

21 January 2018

1 reference

Estrogen: consequences and implications of human mutations in synthesis and action

21 January 2018

1 reference

12 December 2020

Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium

1 reference

12 December 2020

Stromal-epithelial interactions in normal and abnormal prostatic development.

1 reference

12 December 2020

Effects of age, sex steroids, and family relationships on volumes of prostate zones in men with and without prostate cancer

1 reference

12 December 2020

Treating prostate cancer: a rationale for targeting local oestrogens

1 reference

12 December 2020

Estrogen formation in human prostatic tissue from patients with and without benign prostatic hyperplasia

1 reference

12 December 2020

Effect of aging on endogenous level of 5 alpha-dihydrotestosterone, testosterone, estradiol, and estrone in epithelium and stroma of normal and hyperplastic human prostate

1 reference

12 December 2020

Reduced levels of 5-α reductase 2 in adult prostate tissue and implications for BPH therapy

1 reference

12 December 2020

Estrogen reduction by aromatase inhibition for benign prostatic hyperplasia: results of a double-blind, placebo-controlled, randomized clinical trial using two doses of the aromatase-inhibitor atamestane. Atamestane Study Group

1 reference

12 December 2020

Stroma of human benign prostatic hyperplasia: preferential tissue for androgen metabolism and oestrogen binding

1 reference

12 December 2020

Identifiers

DOI

10.1002/PATH.4985

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6212292&resulttype=core&format=json

12 May 2020

PubMed publication ID

28940538

1 reference