Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy (Q34528225)

2 August 2017

Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy (English)

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2 August 2017

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8

Mary-Ellen Taplin

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2 August 2017

Zhenfei Li

1

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2 August 2017

Mohammad Alyamani

2

1 reference

2 August 2017

Jianneng Li

3

1 reference

2 August 2017

Kevin Rogacki

4

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2 August 2017

Mohamed Abazeed

5

1 reference

2 August 2017

Sunil K Upadhyay

6

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2 August 2017

Steven P Balk

7

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2 August 2017

Richard J Auchus

9

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2 August 2017

Nima Sharifi

10

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2 August 2017

language of work or name

English

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publication date

25 May 2016

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2 August 2017

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2 August 2017

533

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2 August 2017

547-551

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2 August 2017

7604

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describes a project that uses

2 August 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/5111629

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nature17954

0 references

cites work

Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5111629

Integrative clinical genomics of advanced prostate cancer

7 July 2018

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HemI: a toolkit for illustrating heatmaps

7 July 2018

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Intense androgen-deprivation therapy with abiraterone acetate plus leuprolide acetate in patients with localized high-risk prostate cancer: results of a randomized phase II neoadjuvant study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5111629

Tumor clone dynamics in lethal prostate cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5111629

Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5111629

Mechanisms of androgen receptor activation in castration-resistant prostate cancer

7 July 2018

1 reference

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A gain-of-function mutation in DHT synthesis in castration-resistant prostate cancer

7 July 2018

1 reference

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Mechanisms of the androgen receptor splicing in prostate cancer cells

7 July 2018

1 reference

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GSVA: gene set variation analysis for microarray and RNA-seq data.

7 July 2018

1 reference

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Abiraterone in metastatic prostate cancer without previous chemotherapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5111629

Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer.

7 July 2018

1 reference

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Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants

7 July 2018

1 reference

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Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer

7 July 2018

1 reference

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Abiraterone and increased survival in metastatic prostate cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5111629

Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5111629

Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5111629

Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5111629

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

7 July 2018

1 reference

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Bioconductor: open software development for computational biology and bioinformatics

7 July 2018

1 reference

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Marked suppression of dihydrotestosterone in men with benign prostatic hyperplasia by dutasteride, a dual 5alpha-reductase inhibitor

7 July 2018

1 reference

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Human type 3 3alpha-hydroxysteroid dehydrogenase (aldo-keto reductase 1C2) and androgen metabolism in prostate cells.

7 July 2018

1 reference

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PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

7 July 2018

1 reference

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Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5111629

LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5111629

Steroid 5 alpha-reductase: two genes/two enzymes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5111629

Arginine 276 controls the directional preference of AKR1C9 (rat liver 3alpha-hydroxysteroid dehydrogenase) in human embryonic kidney 293 cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5111629

Clinical and Biochemical Consequences of CYP17A1 Inhibition with Abiraterone Given with and without Exogenous Glucocorticoids in Castrate Men with Advanced Prostate Cancer

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5111629

Steroid inhibitory effects upon human adrenal 3 beta-hydroxysteroid dehydrogenase activity

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27225130

12 December 2020

inferred from PubMed ID database lookup

1 reference

https://api.crossref.org/works/10.1038%2FNATURE17954

7 January 2021

inferred from DOI database lookup

Development and validation of a novel LC-MS/MS method for simultaneous determination of abiraterone and its seven steroidal metabolites in human serum: Innovation in separation of diastereoisomers without use of a chiral column.

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE17954

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE17954

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Dimensions Publication ID

2 August 2017

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2 August 2017

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