Central role for phosphatidylinositide 3-kinase in the repression of glucose-6-phosphatase gene transcription by insulin. (Q47761737)

5 February 2018

title

Central role for phosphatidylinositide 3-kinase in the repression of glucose-6-phosphatase gene transcription by insulin. (English)

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5 February 2018

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Dickens M

1

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5 February 2018

Svitek CA

2

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Culbert AA

3

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O'Brien RM

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Tavaré JM

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language of work or name

English

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publication date

1 August 1998

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Journal of Biological Chemistry

published in

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volume

273

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5 February 2018

page(s)

20144-20149

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issue

32

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5 February 2018

High levels of glucose-6-phosphatase gene and protein expression reflect an adaptive response in proliferating liver and diabetes

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Glucose regulates in vivo glucose-6-phosphatase gene expression in the liver of diabetic rats.

21 January 2018

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Regulation of rat liver glucose-6-phosphatase gene expression in different nutritional and hormonal states: gene structure and 5'-flanking sequence

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Cloning and sequencing of the 5' region of the human glucose-6-phosphatase gene: transcriptional regulation by cAMP, insulin and glucocorticoids in H4IIE hepatoma cells

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A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6-phosphatase gene transcription by insulin

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Hepatic nuclear factor 3- and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes

21 January 2018

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Identification of a sequence in the PEPCK gene that mediates a negative effect of insulin on transcription

21 January 2018

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Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia

21 January 2018

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Functional analysis of glucocorticoid and insulin response sequences in the rat insulin-like growth factor-binding protein-1 promoter

21 January 2018

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Phosphoinositide 3-kinases: a conserved family of signal transducers

21 January 2018

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IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85

21 January 2018

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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A mammalian protein targeted by G1-arresting rapamycin-receptor complex

21 January 2018

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Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

21 January 2018

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PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

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Regulation of gene expression by insulin

21 January 2018

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Analysis of the signaling pathway involved in the regulation of hexokinase II gene transcription by insulin

21 January 2018

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Peptide substrates suitable for assaying glycogen synthase kinase-3 in crude cell extracts.

21 January 2018

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Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase

21 January 2018

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The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

21 January 2018

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A synthetic inhibitor of the mitogen-activated protein kinase cascade

21 January 2018

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Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma

21 January 2018

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Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

21 January 2018

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The pleckstrin homology domain: an intriguing multifunctional protein module

21 January 2018

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Phosphatidylinositol 3-Kinase, but Not p70/p85 Ribosomal S6 Protein Kinase, Is Required for the Regulation of Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression by Insulin

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.32.20144

1 reference

5 February 2018

PubMed ID

9685358

1 reference

5 February 2018