1,25(OH)2-vitamin D3 enhances the stimulating effect of leucine and insulin on protein synthesis rate through Akt/PKB and mTOR mediated pathways in murine C2C12 skeletal myotubes. (Q47821701)

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scientific article published on 9 August 2013

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English	1,25(OH)2-vitamin D3 enhances the stimulating effect of leucine and insulin on protein synthesis rate through Akt/PKB and mTOR mediated pathways in murine C2C12 skeletal myotubes.	scientific article published on 9 August 2013

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1,25(OH)2-vitamin D3 enhances the stimulating effect of leucine and insulin on protein synthesis rate through Akt/PKB and mTOR mediated pathways in murine C2C12 skeletal myotubes (English)

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7 March 2020

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Philippe Pierre

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Yvette C Luiking

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Yvette C Luiking

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Sjors Verlaan

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Jérôme Salles

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Audrey Chanet

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Christophe Giraudet

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Véronique Patrac

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Marion Jourdan

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Carole Migné

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Yves Boirie

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Stéphane Walrand

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9 August 2013

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Molecular Nutrition and Food Research

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2137-2146

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7 March 2020

Neuromuscular and psychomotor function in elderly subjects who fall and the relationship with vitamin D status.

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Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the Longitudinal Aging Study Amsterdam

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Vitamin D status in relation to one-year risk of recurrent falling in older men and women

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Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials.

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21 January 2018

Is the vitamin d receptor found in muscle?

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Identification of a highly specific and versatile vitamin D receptor antibody

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1,25(OH)2vitamin D3 stimulates myogenic differentiation by inhibiting cell proliferation and modulating the expression of promyogenic growth factors and myostatin in C2C12 skeletal muscle cells

1 reference

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VDR and CYP27B1 are expressed in C2C12 cells and regenerating skeletal muscle: potential role in suppression of myoblast proliferation

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In situ detection of 1,25-dihydroxyvitamin D3 receptor in human skeletal muscle tissue

1 reference

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21 January 2018

1,25-Dihydroxyvitamin D improved the free fatty-acid-induced insulin resistance in cultured C2C12 cells

1 reference

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Physiologic hyperinsulinemia stimulates protein synthesis and enhances transport of selected amino acids in human skeletal muscle

1 reference

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Leucine induces myofibrillar protein accretion in cultured skeletal muscle through mTOR dependent and -independent control of myosin heavy chain mRNA levels.

1 reference

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21 January 2018

A leucine-supplemented diet restores the defective postprandial inhibition of proteasome-dependent proteolysis in aged rat skeletal muscle

1 reference

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21 January 2018

Whole body protein breakdown is less inhibited by insulin, but still responsive to amino acid, in nondiabetic elderly subjects

1 reference

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21 January 2018

Vitamin D: emerging new roles in insulin sensitivity

1 reference

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21 January 2018

Genomic actions of 1,25-dihydroxyvitamin D3 on insulin receptor gene expression, insulin receptor number and insulin activity in the kidney, liver and adipose tissue of streptozotocin-induced diabetic rats

1 reference

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21 January 2018

Dietary intervention with vitamin D, calcium, and whey protein reduced fat mass and increased lean mass in rats

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21 January 2018

Novel insights into the regulation of skeletal muscle protein synthesis as revealed by a new nonradioactive in vivo technique

1 reference

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SUnSET, a nonradioactive method to monitor protein synthesis.

1 reference

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Centrifugation-based isolation of myosin for measurement of its synthesis rate in small muscle samples.

1 reference

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21 January 2018

Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6.

1 reference

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Insulin and IGF-I stimulate the formation of the eukaryotic initiation factor 4F complex and protein synthesis in C2C12 myotubes independent of availability of external amino acids

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21 January 2018

Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts

1 reference

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Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

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High Prevalence of Vitamin D Inadequacy and Implications for Health

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25-hydroxycholecalciferol stimulation of muscle metabolism

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The vitamin D receptor: new paradigms for the regulation of gene expression by 1,25-dihydroxyvitamin D(3).

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21 January 2018

VDR activation of intracellular signaling pathways in skeletal muscle

1 reference

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Identification of a Vitamin D response element in the human insulin receptor gene promoter

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Influence of vitamin D3 deficiency and 1,25 dihydroxyvitamin D3 on de novo insulin biosynthesis in the islets of the rat endocrine pancreas

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Regulation of protein synthesis associated with skeletal muscle hypertrophy by insulin-, amino acid- and exercise-induced signalling

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Molecular mechanisms for the control of translation by insulin

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Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1.

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Low-dose vitamin D prevents muscular atrophy and reduces falls and hip fractures in women after stroke: a randomized controlled trial

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21 January 2018

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