AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance (Q47971254)

7 February 2018

retracted paper

2 references

Dataset for "Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine"

Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

title

AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance (English)

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7 February 2018

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4

Domenico Coppola

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7 February 2018

author name string

Zeng-Qiang Yuan

1

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7 February 2018

Richard I Feldman

2

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7 February 2018

Gene E Sussman

3

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7 February 2018

Santo V Nicosia

5

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7 February 2018

Jin Q Cheng

6

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7 February 2018

language of work or name

English

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publication date

15 April 2003

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7 February 2018

Journal of Biological Chemistry

published in

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7 February 2018

volume

278

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7 February 2018

issue

26

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7 February 2018

page(s)

23432-23440

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7 February 2018

Ovarian cancer: progress and continuing controversies in management

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Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion.

21 January 2018

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High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis

21 January 2018

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Acquired cisplatin resistance in human ovarian cancer cells is associated with enhanced repair of cisplatin-DNA lesions and reduced drug accumulation

21 January 2018

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Introduction of wild-type p53 in a human ovarian cancer cell line not expressing endogenous p53

21 January 2018

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The phosphoinositide 3-kinase pathway

21 January 2018

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

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The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302674200

Mechanism of activation and function of protein kinase B.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302674200

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

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Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

21 January 2018

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Transforming activity and mitosis-related expression of the AKT2 oncogene: evidence suggesting a link between cell cycle regulation and oncogenesis

21 January 2018

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The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis

21 January 2018

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Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells

21 January 2018

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Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress

21 January 2018

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Cisplatin induces a persistent activation of JNK that is related to cell death

21 January 2018

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The stress-activated protein kinase pathways

21 January 2018

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BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

21 January 2018

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Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

21 January 2018

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ASK1 is essential for JNK/SAPK activation by TRAF2

21 January 2018

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Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx

21 January 2018

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Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

21 January 2018

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Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction

21 January 2018

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Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302674200

ASK1 mediates apoptotic cell death induced by genotoxic stress.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M302674200

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

21 January 2018

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AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells

21 January 2018

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Apoptosis-promoting gene (bax) transfer potentiates sensitivity of squamous cell carcinoma to cisplatin in vitro and in vivo

21 January 2018

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Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate

21 January 2018

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The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase

21 January 2018

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The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival

21 January 2018

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Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

21 January 2018

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Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

21 January 2018

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Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.

21 January 2018

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Inhibition of JNK activation through NF-kappaB target genes

21 January 2018

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Cisplatin-induced apoptosis in auditory cells: role of death receptor and mitochondrial pathways

21 January 2018

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Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

21 January 2018

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Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia

21 January 2018

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Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis

21 January 2018

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The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change

21 January 2018

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JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

21 January 2018

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Lack of c-Jun activity increases survival to cisplatin

21 January 2018

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30 December 2023

https://opencitations.net/index/api/v1/references/10.1074/JBC.M302674200

Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1074/JBC.M302674200

Identifiers

DOI

10.1074/JBC.M302674200

1 reference

7 February 2018

PubMed ID

12697749

1 reference

7 February 2018