A small molecule angiotensin II type 2 receptor (AT₂R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 mitogen-activated protein kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia. (Q48039050)

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scientific article published on 6 June 2013

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English	A small molecule angiotensin II type 2 receptor (AT₂R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 mitogen-activated protein kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia.	scientific article published on 6 June 2013

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scholarly article

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2 March 2020

A small molecule angiotensin II type 2 receptor (AT₂R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 mitogen-activated protein kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia (English)

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2 March 2020

neuropathic pain

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2 March 2020

Trent M. Woodruff

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2 March 2020

Arjun Muralidharan

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2 March 2020

Arjun Muralidharan

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2 March 2020

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Bruce D Wyse

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2 March 2020

Thomas Walther

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2 March 2020

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6 June 2013

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2 March 2020

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2 March 2020

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2 March 2020

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2 March 2020

1557-1568

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2 March 2020

The evidence for pharmacological treatment of neuropathic pain

1 reference

https://api.crossref.org/works/10.1111%2FPME.12157

21 January 2018

Small molecule angiotensin II type 2 receptor (AT₂R) antagonists as novel analgesics for neuropathic pain: comparative pharmacokinetics, radioligand binding, and efficacy in rats

1 reference

https://api.crossref.org/works/10.1111%2FPME.12157

21 January 2018

Modulation of net outward current in cultured neurons by angiotensin II: involvement of AT1 and AT2 receptors

1 reference

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21 January 2018

Estrogen elicits dorsal root ganglion axon sprouting via a renin-angiotensin system.

1 reference

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21 January 2018

The angiotensin II type 2 (AT2) receptor: an enigmatic seven transmembrane receptor.

1 reference

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Fire in the hole: pore dilation of the capsaicin receptor TRPV1.

1 reference

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21 January 2018

Role of tyrosine kinase receptors in angiotensin II AT2 receptor signaling: involvement in neurite outgrowth and in p42/p44mapk activation in NG108-15 cells

1 reference

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21 January 2018

Phosphorylation of sodium channel Na(v)1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons

1 reference

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21 January 2018

ERK1/2 mitogen-activated protein kinase phosphorylates sodium channel Na(v)1.7 and alters its gating properties

1 reference

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21 January 2018

Nav1.7 accumulates and co-localizes with phosphorylated ERK1/2 within transected axons in early experimental neuromas.

1 reference

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21 January 2018

Phosphorylation sites on calcium channel alpha1 and beta subunits regulate ERK-dependent modulation of neuronal N-type calcium channels

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21 January 2018

p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia

1 reference

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21 January 2018

Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas.

1 reference

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21 January 2018

Clinical trial of the p38 MAP kinase inhibitor dilmapimod in neuropathic pain following nerve injury.

1 reference

https://api.crossref.org/works/10.1111%2FPME.12157

21 January 2018

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.

1 reference

https://api.crossref.org/works/10.1111%2FPME.12157

21 January 2018

Analgesic efficacy and safety of the novel p38 MAP kinase inhibitor, losmapimod, in patients with neuropathic pain following peripheral nerve injury: a double-blind, placebo-controlled study.

1 reference

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21 January 2018

p38(MAPK): stress responses from molecular mechanisms to therapeutics

1 reference

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21 January 2018

MAPK activation in nociceptive neurons and pain hypersensitivity

1 reference

https://api.crossref.org/works/10.1111%2FPME.12157

21 January 2018

Fyn is involved in angiotensin II type 2 receptor-induced neurite outgrowth, but not in p42/p44mapk in NG108-15 cells

1 reference

https://api.crossref.org/works/10.1111%2FPME.12157

21 January 2018

Intraneuronal angiotensinergic system in rat and human dorsal root ganglia

1 reference

https://api.crossref.org/works/10.1111%2FPME.12157

21 January 2018

Ectopic discharge in Abeta afferents as a source of neuropathic pain

1 reference

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21 January 2018

Bilateral downregulation of Nav1.8 in dorsal root ganglia of rats with bone cancer pain induced by inoculation with Walker 256 breast tumor cells

1 reference

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21 January 2018

Neurotrophic factors and their receptors in human sensory neuropathies

1 reference

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21 January 2018

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