A rho-associated protein kinase, ROKalpha, binds insulin receptor substrate-1 and modulates insulin signaling. (Q48039641)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9468537%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

A rho-associated protein kinase, ROKalpha, binds insulin receptor substrate-1 and modulates insulin signaling (English)

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9 November 2019

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5

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9 November 2019

author name string

S Farah

1

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9 November 2019

Y Agazie

2

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9 November 2019

N Ohan

3

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9 November 2019

J K Ngsee

4

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9 November 2019

language of work or name

English

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publication date

1 February 1998

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Journal of Biological Chemistry

9 November 2019

published in

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9 November 2019

volume

273

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9 November 2019

issue

8

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9 November 2019

page(s)

4740-4746

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Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

9 November 2019

cites work

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Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

21 January 2018

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The PH domain: a common piece in the structural patchwork of signalling proteins

21 January 2018

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A putative modular domain present in diverse signaling proteins

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Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice

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The function of KGF in morphogenesis of epithelium and reepithelialization of wounds

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PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities

21 January 2018

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Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor

21 January 2018

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The pleckstrin homology domain in insulin receptor substrate-1 sensitizes insulin signaling

21 January 2018

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The pleckstrin homology domain is the principal link between the insulin receptor and IRS-1.

21 January 2018

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Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity

21 January 2018

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Distinct modes of interaction of SHC and insulin receptor substrate-1 with the insulin receptor NPEY region via non-SH2 domains

21 January 2018

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Interaction of insulin receptor substrate-2 (IRS-2) with the insulin and insulin-like growth factor I receptors. Evidence for two distinct phosphotyrosine-dependent interaction domains within IRS-2

21 January 2018

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14-3-3 (epsilon) interacts with the insulin-like growth factor I receptor and insulin receptor substrate I in a phosphoserine-dependent manner

21 January 2018

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14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain

21 January 2018

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Molecular cloning of an amphibian insulin receptor substrate 1-like cDNA and involvement of phosphatidylinositol 3-kinase in insulin-induced Xenopus oocyte maturation

21 January 2018

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Role of IRS-2 in insulin and cytokine signalling

21 January 2018

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The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate family

21 January 2018

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A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family

21 January 2018

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Microinjection of a protein-tyrosine-phosphatase inhibits insulin action in Xenopus oocytes

21 January 2018

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Effect of microinjection of a low-Mr human placenta protein tyrosine phosphatase on induction of meiotic cell division in Xenopus oocytes

21 January 2018

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Identification and cloning of localized maternal RNAs from Xenopus eggs

21 January 2018

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Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate

21 January 2018

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Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

21 January 2018

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The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton

21 January 2018

1 reference

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Requirements for Phosphorylation of Map Kinase During Meiosis in Xenopus Oocytes

21 January 2018

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A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes

21 January 2018

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Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

21 January 2018

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

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Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II.

21 January 2018

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Tyrosine phosphorylation and activation of homologous protein kinases during oocyte maturation and mitogenic activation of fibroblasts

21 January 2018

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Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes

21 January 2018

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Rho: a connection between membrane receptor signalling and the cytoskeleton

21 January 2018

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Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

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Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins

21 January 2018

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MAP kinase- and Rho-dependent signals interact to regulate gene expression but not actin morphology in cardiac muscle cells

21 January 2018

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Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase.

21 January 2018

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The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

21 January 2018

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High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif

21 January 2018

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IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.8.4740

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9468537%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference