Low hippocampal PI(4,5)P₂ contributes to reduced cognition in old mice as a result of loss of MARCKS. (Q48151677)

9 February 2018

title

Low hippocampal PI(4,5)P₂ contributes to reduced cognition in old mice as a result of loss of MARCKS. (English)

1 reference

9 February 2018

author

Claudia Bagni

5

1 reference

9 February 2018

author name string

Laura Trovò

1

1 reference

9 February 2018

Tariq Ahmed

2

1 reference

9 February 2018

Zsuzsanna Callaerts-Vegh

3

1 reference

9 February 2018

Andrea Buzzi

4

1 reference

9 February 2018

Marinee Chuah

6

1 reference

9 February 2018

Thierry Vandendriessche

7

1 reference

9 February 2018

Rudi D'Hooge

8

1 reference

9 February 2018

Detlef Balschun

9

1 reference

9 February 2018

Carlos G Dotti

10

1 reference

9 February 2018

language of work or name

English

0 references

publication date

24 February 2013

1 reference

9 February 2018

published in

Nature Neuroscience

1 reference

9 February 2018

volume

16

1 reference

9 February 2018

issue

4

1 reference

9 February 2018

page(s)

449-455

1 reference

9 February 2018

Life and death of neurons in the aging brain

cites work

1 reference

The aging brain: morphomolecular senescence of cortical circuits

21 January 2018

1 reference

Cholesterol synthesis rate in human hippocampus declines with aging.

21 January 2018

1 reference

Changes in weight and compositions of major membrane components of human brain during the span of adult human life of Swedes

21 January 2018

1 reference

Sphingomyelin upregulation in mature neurons contributes to TrkB activity by Rac1 endocytosis.

21 January 2018

1 reference

Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking

21 January 2018

1 reference

Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2

21 January 2018

1 reference

Role of phosphoinositides at the neuronal synapse

21 January 2018

1 reference

Phosphoinositides in cell regulation and membrane dynamics

21 January 2018

1 reference

Calcium stores and synaptic plasticity

21 January 2018

1 reference

Calcium regulation of neuronal gene expression

21 January 2018

1 reference

Cholesterol loss during glutamate-mediated excitotoxicity

21 January 2018

1 reference

Regulation of phosphoinositide-specific phospholipase C

21 January 2018

1 reference

Fodrin inhibits phospholipases A2, C, and D by decreasing polyphosphoinositide cell content

21 January 2018

1 reference

Myristoylated alanine-rich C kinase substrate (MARCKS) produces reversible inhibition of phospholipase C by sequestering phosphatidylinositol 4,5-bisphosphate in lateral domains.

21 January 2018

1 reference

Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover

21 January 2018

1 reference

Plasma membrane phosphoinositide organization by protein electrostatics

21 January 2018

1 reference

Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brain

21 January 2018

1 reference

Calcium homeostasis and modulation of synaptic plasticity in the aged brain

21 January 2018

1 reference

Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store

21 January 2018

1 reference

Alterations in intrinsic neuronal excitability during normal aging.

21 January 2018

1 reference

Hippocampal long-term potentiation is supported by presynaptic and postsynaptic tyrosine receptor kinase B-mediated phospholipase Cgamma signaling.

21 January 2018

1 reference

Phospholipase C is required for changes in postsynaptic structure and function associated with NMDA receptor-dependent long-term depression

21 January 2018

1 reference

Myristoylated alanine rich C kinase substrate (MARCKS) heterozygous mutant mice exhibit deficits in hippocampal mossy fiber-CA3 long-term potentiation.

21 January 2018

1 reference

Effect of reduced myristoylated alanine-rich C kinase substrate expression on hippocampal mossy fiber development and spatial learning in mutant mice: transgenic rescue and interactions with gene background

21 January 2018

1 reference

The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 region of the hippocampus.

21 January 2018

1 reference

Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitro

21 January 2018

1 reference

Membrane lipids in the aging human brain

21 January 2018

1 reference

MARCKS regulates lamellipodia formation induced by IGF-I via association with PIP2 and beta-actin at membrane microdomains.

21 January 2018

1 reference

The MARCKS protein plays a critical role in phosphatidylinositol 4,5-bisphosphate metabolism and directed cell movement in vascular endothelial cells

21 January 2018

1 reference

Presenilin mutations linked to familial Alzheimer's disease cause an imbalance in phosphatidylinositol 4,5-bisphosphate metabolism

21 January 2018

1 reference

Oligomeric amyloid-beta peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolism

21 January 2018

1 reference

Regulation of postsynaptic AMPA responses by synaptojanin 1

21 January 2018

1 reference

EphrinB-EphB signalling regulates clathrin-mediated endocytosis through tyrosine phosphorylation of synaptojanin 1

21 January 2018

1 reference

Coupling exo- and endocytosis: an essential role for PIP₂ at the synapse.

21 January 2018

1 reference

Solution single-vesicle assay reveals PIP2-mediated sequential actions of synaptotagmin-1 on SNAREs

21 January 2018

1 reference

Essential role of phosphoinositide metabolism in synaptic vesicle recycling

21 January 2018

1 reference

A reciprocal interdependence between Nck and PI(4,5)P(2) promotes localized N-WASp-mediated actin polymerization in living cells

21 January 2018

1 reference

Actin filament assembly by myristoylated alanine-rich C kinase substrate-phosphatidylinositol-4,5-diphosphate signaling is critical for dendrite branching

21 January 2018

1 reference

GAP43, MARCKS, and CAP23 modulate PI(4,5)P(2) at plasmalemmal rafts, and regulate cell cortex actin dynamics through a common mechanism

21 January 2018

1 reference

Essential role for the PKC target MARCKS in maintaining dendritic spine morphology

21 January 2018

1 reference

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

Akt phosphorylation and neuronal survival after traumatic brain injury in mice

21 January 2018

1 reference

Neuronal polarity: essential role of protein-lipid complexes in axonal sorting

21 January 2018

1 reference

Profilin2 contributes to synaptic vesicle exocytosis, neuronal excitability, and novelty-seeking behavior

21 January 2018

1 reference

The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP

21 January 2018

1 reference

Nonradioactive methods for the assay of phosphoinositide 3-kinases and phosphoinositide phosphatases and selective detection of signaling lipids in cell and tissue extracts

21 January 2018

1 reference

Overexpression of the myristoylated alanine-rich C-kinase substrate inhibits cell adhesion to extracellular matrix components

21 January 2018

1 reference

Spred1 is required for synaptic plasticity and hippocampus-dependent learning

21 January 2018

1 reference

Applications of the Morris water maze in the study of learning and memory

21 January 2018

1 reference

Generalization of fear responses in C57BL/6N mice subjected to one-trial foreground contextual fear conditioning

21 January 2018

1 reference

Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal

21 January 2018

1 reference

12 December 2020

Evidence that increased hippocampal expression of the cytokine interleukin-1 beta is a common trigger for age- and stress-induced impairments in long-term potentiation.

1 reference

12 December 2020

Novel function of phosphatidylinositol 4,5-bisphosphate as a cofactor for brain membrane phospholipase D

1 reference

12 December 2020

MARCKS, membranes, and calmodulin: kinetics of their interaction

1 reference

12 December 2020

The ageing cortical synapse: hallmarks and implications for cognitive decline

1 reference

12 December 2020

Membrane lipids of adult human brain: lipid composition of frontal and temporal lobe in subjects of age 20 to 100 years.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NN.3342

1 reference

9 February 2018

1 reference

9 February 2018