Caveolin-3 upregulation activates beta-secretase-mediated cleavage of the amyloid precursor protein in Alzheimer's disease. (Q48157199)

9 February 2018

title

Caveolin-3 upregulation activates beta-secretase-mediated cleavage of the amyloid precursor protein in Alzheimer's disease. (English)

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9 February 2018

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Nishiyama K

1

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9 February 2018

Trapp BD

2

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Ikezu T

3

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Ransohoff RM

4

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Tomita T

5

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Iwatsubo T

6

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Kanazawa I

7

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Hsiao KK

8

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Lisanti MP

9

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Okamoto T

10

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language of work or name

English

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publication date

1 August 1999

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9 February 2018

published in

Journal of Neuroscience

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volume

19

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issue

15

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page(s)

6538-6548

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Amyloid load and neural elements in Alzheimer's disease and nondemented individuals with high amyloid plaque density.

cites work

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Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins

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Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

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Expression of caveolin-1 and -2 in differentiating PC12 cells and dorsal root ganglion neurons: caveolin-2 is up-regulated in response to cell injury

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Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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Axonal amyloid precursor protein expressed by neurons in vitro is present in a membrane fraction with caveolae-like properties.

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Protease inhibitors generate cytotoxic fragments from Alzheimer amyloid protein precursor in cDNA-transfected glioma cells

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Functional rafts in cell membranes

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VIP21, a 21-kD membrane protein is an integral component of trans-Golgi-network-derived transport vesicles

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Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe

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12 December 2020

Soluble derivatives of the beta amyloid protein precursor in cerebrospinal fluid: alterations in normal aging and in Alzheimer's disease

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12 December 2020

Tyrosine kinase receptors concentrated in caveolae-like domains from neuronal plasma membrane

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12 December 2020

Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease

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12 December 2020

Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle

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12 December 2020

Complementary DNA for the mouse homolog of the human amyloid beta protein precursor.

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12 December 2020

Identifiers

PubMed ID

10414982

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9 February 2018