Peroxisome proliferator-activated receptor-γ (PPAR-γ) activation confers functional neuroprotection in global ischemia (Q48176203)

9 February 2018

title

Peroxisome proliferator-activated receptor-γ (PPAR-γ) activation confers functional neuroprotection in global ischemia (English)

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9 February 2018

author name string

Zahra Fatehi-Hassanabad

series ordinal

1

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9 February 2018

R A Tasker

series ordinal

2

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9 February 2018

publication date

4 June 2010

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9 February 2018

published in

Neurotoxicity Research

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9 February 2018

volume

19

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9 February 2018

issue

3

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9 February 2018

page(s)

462-471

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9 February 2018

PPAR gamma ligands, rosiglitazone and pioglitazone, inhibit bFGF- and VEGF-mediated angiogenesis.

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Delayed post ischemic treatment with Rosiglitazone attenuates infarct volume, neurological deficits and neutrophilia after embolic stroke in rat.

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Inflammatory mediators and stroke: new opportunities for novel therapeutics

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Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain

21 January 2018

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Selective activation of peroxisome proliferator-activated receptor (PPAR)alpha and PPAR gamma induces neoangiogenesis through a vascular endothelial growth factor-dependent mechanism.

21 January 2018

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Pioglitazone enhances collateral blood flow in ischemic hindlimb of diabetic mice through an Akt-dependent VEGF-mediated mechanism, regardless of PPARgamma stimulation.

21 January 2018

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Peroxisome proliferator-activated receptors and angiogenesis.

21 January 2018

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Increased plasma levels of 15-deoxyDelta prostaglandin J2 are associated with good outcome in acute atherothrombotic ischemic stroke.

21 January 2018

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Sensorimotor and cognitive deficits after transient middle cerebral artery occlusion in the mouse.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Assessment of the relative contribution of COX-1 and COX-2 isoforms to ischemia-induced oxidative damage and neurodegeneration following transient global cerebral ischemia.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Effects of rosiglitazone on global ischemia-induced hippocampal injury and expression of mitochondrial uncoupling protein 2.

21 January 2018

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21 January 2018

Excitotoxic cell death

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https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Peroxisome proliferator-activated receptor-gamma-agonist, rosiglitazone, promotes angiogenesis after focal cerebral ischemia

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Modulation of the oxidative stress and inflammatory response by PPAR-gamma agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Peroxisome proliferator-activated receptors (PPARs) and peroxisomes in rat cortical and cerebellar astrocytes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Peroxisome proliferator-activated receptors (PPARs) and related transcription factors in differentiating astrocyte cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor exert additive anti-inflammatory effects on experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

The effect of bilateral carotid artery ligation upon the blood flow and the energy state of the rat brain

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Evolving stroke and the ischemic penumbra

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Peroxisome proliferator-activated receptor gamma up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Antagonists of excitatory amino acids and endogenous opioid peptides in the treatment of experimental central nervous system injury

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Changes in extracellular amino acid neurotransmitters produced by focal cerebral ischemia

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Elevation of plasma nitric oxide end products during focal cerebral ischemia and reperfusion in the rat.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Expression and function of PPARgamma in rat and human vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

PPARgamma agonist pioglitazone reduces matrix metalloproteinase-9 activity and neuronal damage after focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Neuroprotection against focal ischemic brain injury by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

The role of neuroimmunomodulation in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

The ubiquitin-proteasome system contributes to the inflammatory injury in ischemic diabetic myocardium: the role of glycemic control

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Intensity of chronic cerebral hypoperfusion determines white/gray matter injury and cognitive/motor dysfunction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Time-dependent effects of global cerebral ischemia on anxiety, locomotion, and habituation in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

NMDA receptor-dependent excitotoxicity: the role of intracellular Ca2+ release

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Multimodal assessment of neuroprotection applied to the use of MK-801 in the endothelin-1 model of transient focal brain ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Characterization of cellular and neurological damage following unilateral hypoxia/ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Troglitazone inhibits vascular endothelial growth factor-induced angiogenic signaling via suppression of reactive oxygen species production and extracellular signal-regulated kinase phosphorylation in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

PPARgamma : a nuclear regulator of metabolism, differentiation, and cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Neuroinflammation and neuroprotective strategies in acute ischaemic stroke - from bench to bedside.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Endothelin-1 induced middle cerebral artery occlusion: pathological consequences and neuroprotective effects of MK801.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

A peroxisome proliferator-activated receptor-gamma agonist reduces infarct size in transient but not in permanent ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: implications for multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Nitric oxide in cerebral ischemic neurodegeneration and excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Effectiveness of PSD95 inhibitors in permanent and transient focal ischemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Peroxisome proliferator-activated receptor-gamma ligands reduce inflammation and infarction size in transient focal ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Inhibition by spermine of the induction of nitric oxide synthase in J774.2 macrophages: requirement of a serum factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Activated phosphorylation of cyclic AMP response element binding protein is associated with preservation of striatal neurons after focal cerebral ischemia in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Activating peroxisome proliferator-activated receptor gamma mutant promotes tumor growth in vivo by enhancing angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Inflammatory cytokines in acute ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Troglitazone inhibits both post-glutamate neurotoxicity and low-potassium-induced apoptosis in cerebellar granule neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Lipid peroxidation in rat cerebral cortex during post-ischemic reperfusion: effect of exogenous antioxidants and Ca(++)-antagonist drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

ATF-2 phosphorylation in apoptotic neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Rosiglitazone alone or in combination with tissue plasminogen activator improves ischemic brain injury in an embolic model in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Oxidants, antioxidants and the ischemic brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Reduction of vasogenic edema and infarction by MK-801 in rats after temporary focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

Neuronal PPARgamma deficiency increases susceptibility to brain damage after cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-010-9201-3

PDEs as drug targets for CNS immune disorders.

21 January 2018

1 reference

12 December 2020

PPARgamma agonists inhibit angiogenesis by suppressing PKCalpha- and CREB-mediated COX-2 expression in the human endothelium.

1 reference

12 December 2020

Role of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and its natural ligand 15-deoxy-Delta12, 14-prostaglandin J2 in the regulation of microglial functions

1 reference

12 December 2020

Antiinflammatory properties of PPARgamma agonists following ischemia.

1 reference

12 December 2020

Effect of cypermethrin on memory, movement activity and coordination in mice after transient incomplete cerebral ischemia.

1 reference

12 December 2020

Delayed treatment with AM-36, a novel neuroprotective agent, reduces neuronal damage after endothelin-1-induced middle cerebral artery occlusion in conscious rats

1 reference

12 December 2020

Functional assessments in mice and rats after focal stroke

1 reference

12 December 2020

Neuroprotective effects of estrogen treatment on ischemia-induced behavioural deficits in ovariectomized gerbils at different ages.

1 reference

12 December 2020

CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injury

1 reference

12 December 2020

Rosiglitazone induces mitochondrial biogenesis in mouse brain.

1 reference

12 December 2020

The PPAR-gamma Agonist 15-Deoxy-Delta-Prostaglandin J(2) Attenuates Microglial Production of IL-12 Family Cytokines: Potential Relevance to Alzheimer's Disease

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12 December 2020

Effects of thiazolidinediones on stroke recovery: a case-matched controlled study

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12 December 2020

Ischemic cell death in brain neurons

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12 December 2020

The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses

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12 December 2020

10.1007/S12640-010-9201-3

Identifiers

DOI

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9 February 2018

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9 February 2018