Endogenous bax translocation in SH-SY5Y human neuroblastoma cells and cerebellar granule neurons undergoing apoptosis. (Q48227531)

9 February 2018

title

Endogenous bax translocation in SH-SY5Y human neuroblastoma cells and cerebellar granule neurons undergoing apoptosis. (English)

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9 February 2018

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author name string

McGinnis KM

series ordinal

1

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9 February 2018

Gnegy ME

series ordinal

2

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language of work or name

English

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publication date

1 May 1999

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9 February 2018

Journal of Neurochemistry

number of pages

8

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based on heuristic

inferred from page(s)

published in

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volume

72

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issue

5

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9 February 2018

page(s)

1899-1906

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9 February 2018

Characterization of the cell death process induced by staurosporine in human neuroblastoma cell lines

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Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

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Conversion of Bcl-2 to a Bax-like death effector by caspases

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BAX is required for neuronal death after trophic factor deprivation and during development

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Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

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Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions

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MPP+ induced SH-SY5Y apoptosis is potentiated by cyclosporin A and inhibited by aristolochic acid

21 January 2018

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Potassium deprivation-induced apoptosis of cerebellar granule neurons: cytochrome c release in the absence of altered expression of Bcl-2 family proteins.

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Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

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Regulated targeting of BAX to mitochondria.

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Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

21 January 2018

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Nitric oxide induces apoptosis via triggering mitochondrial permeability transition.

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Bax directly induces release of cytochrome c from isolated mitochondria

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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

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Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death.

21 January 2018

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Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis

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Alzheimer's amyloid precursor protein alpha-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: similarities to the angiotensin converting enzyme secretase

21 January 2018

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Double identity for proteins of the Bcl-2 family

21 January 2018

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1-(5-Isoquinolinesulfonyl)-2-methylpiperazine induces apoptosis in human neuroblastoma cells, SH-SY5Y, through a p53-dependent pathway

21 January 2018

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21 January 2018

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Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

21 January 2018

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A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

21 January 2018

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Priming of cultured neurons with sabeluzole results in long-lasting inhibition of neurotoxin-induced tau expression and cell death

21 January 2018

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Bcl-2, Bax and Bcl-x expression in neuronal apoptosis: a study of mutant weaver and lurcher mice.

21 January 2018

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G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP.

21 January 2018

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

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Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

21 January 2018

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Injected cytochrome c induces apoptosis

21 January 2018

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

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Alterations of Extracellular Calcium Elicit Selective Modes of Cell Death and Protease Activation in SH-SY5Y Human Neuroblastoma Cells

21 January 2018

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Death cycle and Swiss army knives

21 January 2018

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10.1046/J.1471-4159.1999.0721899.X

21 January 2018

Identifiers

DOI

1 reference

9 February 2018

PubMed ID

10217266

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9 February 2018