The gyrase inhibitor albicidin consists of p-aminobenzoic acids and cyanoalanine. (Q48234455)

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28 February 2020

title

The gyrase inhibitor albicidin consists of p-aminobenzoic acids and cyanoalanine (English)

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28 February 2020

main subject

Xanthomonas albilineans

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17

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28 February 2020

Stéphane Cociancich

1

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28 February 2020

Alexander Pesic

2

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28 February 2020

Daniel Petras

3

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28 February 2020

Sebastian Kemper

13

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28 February 2020

author name string

Stefanie Uhlmann

4

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28 February 2020

Julian Kretz

5

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28 February 2020

Vivien Schubert

6

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28 February 2020

Laura Vieweg

7

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28 February 2020

Sandrine Duplan

8

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28 February 2020

Mélanie Marguerettaz

9

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28 February 2020

Julie Noëll

10

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28 February 2020

Isabelle Pieretti

11

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28 February 2020

Manuela Hügelland

12

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28 February 2020

Andi Mainz

14

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28 February 2020

Philippe Rott

15

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28 February 2020

Monique Royer

16

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28 February 2020

publication date

19 January 2015

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28 February 2020

published in

Nature Chemical Biology

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28 February 2020

volume

11

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issue

3

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page(s)

195-197

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https://scigraph.springernature.com/pub.10.1038/nchembio.1734

28 February 2020

exact match

0 references

cites work

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Albicidin pathotoxin produced by Xanthomonas albilineans is encoded by three large PKS and NRPS genes present in a gene cluster also containing several putative modifying, regulatory, and resistance genes

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The phytotoxin albicidin is a novel inhibitor of DNA gyrase.

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The ATP-binding site of type II topoisomerases as a target for antibacterial drugs

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Heterologous production of albicidin: a promising approach to overproducing and characterizing this potent inhibitor of DNA gyrase.

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21 January 2018

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The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase

21 January 2018

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Monophyly of class I aminoacyl tRNA synthetase, USPA, ETFP, photolyase, and PP-ATPase nucleotide-binding domains: implications for protein evolution in the RNA.

21 January 2018

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Analysis of the genes flanking xabB: a methyltransferase gene is involved in albicidin biosynthesis in Xanthomonas albilineans

21 January 2018

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Crystal structure of the termination module of a nonribosomal peptide synthetase

21 January 2018

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The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases

21 January 2018

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Factors affecting biosynthesis by Xanthomonas albilineans of albicidin antibiotics and phytotoxins.

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Conformational Switches Modulate Protein Interactions in Peptide Antibiotic Synthetases

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Preliminary characterization of an antibiotic produced by Xanthomonas albilineans which inhibits DNA synthesis in Escherichia coli.

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25599532

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO.1734

1 reference

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28 February 2020

1 reference