Chapter 8. Methods for in silico prediction of microbial polyketide and nonribosomal peptide biosynthetic pathways from DNA sequence data (Q33431525)

26 July 2017

Chapter 8. Methods for in silico prediction of microbial polyketide and nonribosomal peptide biosynthetic pathways from DNA sequence data (English)

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26 July 2017

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2

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26 July 2017

1

Brian O Bachmann

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PubMed ID

19374984

26 July 2017

language of work or name

English

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publication date

1 January 2009

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26 July 2017

Methods in Enzymology

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26 July 2017

458

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26 July 2017

181-217

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Structural basis for macrolactonization by the pikromycin thioesterase

26 July 2017

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Basic local alignment search tool

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

NRPS-PKS: a knowledge-based resource for analysis of NRPS/PKS megasynthases

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

[25] Protein multiple sequence alignment and flexible pattern matching

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

6-Deoxyerythronolide-B synthase 2 from Saccharopolyspora erythraea. Cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Conserved amino acid residues correlating with ketoreductase stereospecificity in modular polyketide synthases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Genome mining for novel natural product discovery

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Mining microbial genomes for new natural products and biosynthetic pathways

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Using genomics to deliver natural products from symbiotic bacteria

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Active-site residue, domain and module swaps in modular polyketide synthases

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Structure elucidation and biosynthesis of fuscachelins, peptide siderophores from the moderate thermophile Thermobifida fusca

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Organization of the enzymatic domains in the multifunctional polyketide synthase involved in erythromycin formation in Saccharopolyspora erythraea

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Profile hidden Markov models

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Scores for sequence searches and alignments

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Benzodiazepine biosynthesis in Streptomyces refuineus.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

InterPro: the integrative protein signature database

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Charting biologically relevant chemical space: a structural classification of natural products (SCONP)

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Compound library development guided by protein structure similarity clustering and natural product structure

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Structural and functional characterization of gene clusters directing nonribosomal synthesis of bioactive cyclic lipopeptides in Bacillus amyloliquefaciens strain FZB42

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Characterization of the saframycin A gene cluster from Streptomyces lavendulae NRRL 11002 revealing a nonribosomal peptide synthetase system for assembling the unusual tetrapeptidyl skeleton in an iterative manner

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

CDD: specific functional annotation with the Conserved Domain Database

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

CD-Search: protein domain annotations on the fly

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Carrier protein recognition in siderophore-producing nonribosomal peptide synthetases

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

BLAST: at the core of a powerful and diverse set of sequence analysis tools

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Evolutionary affiliations within the superfamily of ketosynthases reflect complex pathway associations.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Critical assessment of methods of protein structure prediction-Round VII

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

In silico characterization of proteins: UniProt, InterPro and Integr8.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Improved tools for biological sequence comparison

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Substrate specificity of the acyl transferase domains of EpoC from the epothilone polyketide synthase

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs)

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

In vivo characterization of tandem C-terminal thioesterase domains in arthrofactin synthetase.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Trading molecules and tracking targets in symbiotic interactions

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Redesign of the coenzyme specificity of a dehydrogenase by protein engineering

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

The Escherichia coli malonyl-CoA:acyl carrier protein transacylase at 1.5-A resolution. Crystal structure of a fatty acid synthase component

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Cloning and characterization of the bleomycin biosynthetic gene cluster from Streptomyces verticillus ATCC15003.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

The type I fatty acid and polyketide synthases: a tale of two megasynthases

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Identification of common molecular subsequences

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Polyketide biosynthesis: a millennium review

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Crystal structure of the termination module of a nonribosomal peptide synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Identification of protein sequence homology by consensus template alignment

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Non-colinear polyketide biosynthesis in the aureothin and neoaureothin pathways: an evolutionary perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

SEARCHPKS: A program for detection and analysis of polyketide synthase domains.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2809%2904808-3

7 January 2021

10.1016/S0076-6879(09)04808-3

Identifiers

DOI

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release_w2yp57iambh67c3l5t6h4zsxom

26 July 2017

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Fatcat

https://api.fatcat.wiki/v0/release/w2yp57iambh67c3l5t6h4zsxom

24 November 2022

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PubMed ID

19374984

1 reference

PubMed ID

19374984