Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways (Q48294439)

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English	Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

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Robert J. Homer

2

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

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Chun Geun Lee

1

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Barney S. Graham

7

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Barney S Graham

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

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Lauren Cohn

3

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

Holger Link

4

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

Sungsoo Jung

5

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

Joseph E Craft

6

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

Teresa R Johnson

8

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

Jack A Elias

9

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

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publication date

9 July 2002

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

277

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

38

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

35466-35474

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Macrophage deactivation by interleukin 10

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

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Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia

1 reference

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Ca(2+)-dependent activation of Cl(-) currents in Xenopus oocytes is modulated by voltage

1 reference

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Interleukin-10 induces E-selectin on small and large blood vessel endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Interleukin 10 inhibits lipopolysaccharide-induced survival and cytokine production by human peripheral blood eosinophils

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Interleukin-10 inhibits antigen-induced cellular recruitment into the airways of sensitized mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

IL-11 selectively inhibits aeroallergen-induced pulmonary eosinophilia and Th2 cytokine production.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Cystic fibrosis mice lacking Muc1 have reduced amounts of intestinal mucus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Complete sequence of the human mucin MUC4: a putative cell membrane-associated mucin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Role of gob-5 in mucus overproduction and airway hyperresponsiveness in asthma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Characterization of a calcium-activated chloride channel as a shared target of Th2 cytokine pathways and its potential involvement in asthma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Role of Interleukin-10 in the Lung Response to Silica in Mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

IL-10 is necessary and sufficient for autoimmune diabetes in conjunction with NOD MHC homozygosity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Suppression of asthma-like responses in different mouse strains by oral tolerance.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

The relationship between atopic status and IL-10 nasal lavage levels in the acute and persistent inflammatory response to upper respiratory tract infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Net inflammatory capacity of human septic shock plasma evaluated by a monocyte-based target cell assay: identification of interleukin-10 as a major functional deactivator of human monocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Leukocyte extravasation into the pancreatic tissue in transgenic mice expressing interleukin 10 in the islets of Langerhans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Interleukin 10 increases CCR5 expression and HIV infection in human monocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Allergen-induced IL-9 directly stimulates mucin transcription in respiratory epithelial cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Localization of two distinct type III phosphatidylinositol 4-kinase enzyme mRNAs in the rat.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Monocyte IL-10 production during respiratory syncytial virus bronchiolitis is associated with recurrent wheezing in a one-year follow-up study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Interleukin-13: central mediator of allergic asthma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206395200

21 January 2018

Identifiers

10.1074/JBC.M206395200

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/12107190

ResearchGate publication ID

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