Blood-brain barrier alterations in the cerebral cortex in experimental autoimmune encephalomyelitis (Q48366273)

11 February 2018

title

Blood-brain barrier alterations in the cerebral cortex in experimental autoimmune encephalomyelitis (English)

1 reference

11 February 2018

1 reference

10

1 reference

11 February 2018

Giovanni Ferrara

Giovanni Ferrara

3

0 references

Valentina Boldrin

Valentina Boldrin

6

0 references

Francesco Girolamo

Francesco Girolamo

2

0 references

Antonio Uccelli

Antonio Uccelli

8

0 references

Mario Salmona

Mario Salmona

11

0 references

Mariella Errede

1

Mariella Errede

1 reference

11 February 2018

author name string

Maurizio Strippoli

4

1 reference

11 February 2018

Sara Morando

5

1 reference

11 February 2018

Marco Rizzi

7

1 reference

11 February 2018

Roberto Perris

9

1 reference

11 February 2018

Luisa Roncali

12

1 reference

11 February 2018

Daniela Virgintino

13

1 reference

11 February 2018

publication date

1 October 2012

1 reference

11 February 2018

Journal of Neuropathology & Experimental Neurology

published in

1 reference

11 February 2018

volume

71

1 reference

11 February 2018

issue

10

1 reference

11 February 2018

page(s)

840-854

1 reference

11 February 2018

Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research.

cites work

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Experimental models of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Animal models of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Experimental allergic encephalomyelitis: a misleading model of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Loss of blood-brain barrier integrity in the spinal cord is common to experimental allergic encephalomyelitis in knockout mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Translational research in neurology and neuroscience 2010: multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Claudin-1 induced sealing of blood-brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Multiple sclerosis: distribution of inflammatory cells in newly forming lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis. Pathogenetic and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Abnormal endothelial tight junctions in active lesions and normal-appearing white matter in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

The blood-brain barrier/neurovascular unit in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Persistent endothelial abnormalities and blood-brain barrier leak in primary and secondary progressive multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

The blood-brain barrier in health and chronic neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

The effects of blood-brain barrier disruption on glial cell function in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Beyond blood brain barrier breakdown - in vivo detection of occult neuroinflammatory foci by magnetic nanoparticles in high field MRI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

The blood-brain barrier in brain homeostasis and neurological diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Tight junctions of the blood-brain barrier: development, composition and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Structure and function of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Tight junctional abnormality in multiple sclerosis white matter affects all calibres of vessel and is associated with blood-brain barrier leakage and active demyelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Angiotensin II controls occludin function and is required for blood brain barrier maintenance: relevance to multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

A spatial analysis of the blood-brain barrier damage in experimental allergic encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Blood-brain barrier disruption in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Blood-brain barrier permeability and monocyte infiltration in experimental allergic encephalomyelitis: a quantitative MRI study

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Inflammation and dephosphorylation of the tight junction protein occludin in an experimental model of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Loss of astrocyte polarity marks blood-brain barrier impairment during experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Blood-brain barrier disruption and enhanced vascular permeability in the multiple sclerosis model EAE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Evidence of early cortical atrophy in MS: relevance to white matter changes and disability

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Grey matter pathology in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Gray matter involvement in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Cortical pathology in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Cortical lesions and atrophy associated with cognitive impairment in relapsing-remitting multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Gray matter pathology in (chronic) MS: modern views on an early observation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Demyelination, inflammation, and neurodegeneration in multiple sclerosis deep gray matter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Gray matter pathology and multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Improved in vivo detection of cortical lesions in multiple sclerosis using double inversion recovery MR imaging at 3 Tesla

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

The blood-brain barrier in cortical multiple sclerosis lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Demyelinated neocortical lesions in marmoset autoimmune encephalomyelitis mimic those in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

A new focal EAE model of cortical demyelination: multiple sclerosis-like lesions with rapid resolution of inflammation and extensive remyelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Cortical demyelination can be modeled in specific rat models of autoimmune encephalomyelitis and is major histocompatibility complex (MHC) haplotype-related.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Cerebral cortex demyelination and oligodendrocyte precursor response to experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

An animal model of cortical and callosal pathology in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Blood-brain barrier disruption and lesion localisation in experimental autoimmune encephalomyelitis with predominant cerebellar and brainstem involvement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Pertussis toxin transiently affects barrier integrity, organelle organization and transmigration of monocytes in a human brain microvascular endothelial cell barrier model

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Differential expression of CD45 on canine microglial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Differences in expression of junctional adhesion molecule-A and beta-catenin in multiple sclerosis brain tissue: increasing evidence for the role of tight junction pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Multiple sclerosis and cerebral endothelial dysfunction: Mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Tumour necrosis factor and lymphotoxin: molecular aspects and role in tissue-specific autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Microglia in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Cytokine regulation of tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Blood brain barrier compromise with endothelial inflammation may lead to autoimmune loss of myelin during multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Tight junctions in brain barriers during central nervous system inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Radical changes in multiple sclerosis pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Dysferlin is a new marker for leaky brain blood vessels in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Spatial diversity of blood-brain barrier alteration and macrophage invasion in experimental autoimmune encephalomyelitis: a comparative MRI study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: evidence for the existence of an immunological brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

21 January 2018

Glia-T cell dialogue.

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Astrocyte-induced T cell elimination is CD95 ligand dependent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Extensive extracellular matrix depositions in active multiple sclerosis lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Endothelial basement membrane laminin alpha5 selectively inhibits T lymphocyte extravasation into the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

The proteome of mouse brain microvessel membranes and basal lamina

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Review: leucocyte-endothelial cell crosstalk at the blood-brain barrier: a prerequisite for successful immune cell entry to the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Vascular permeability in ocular disease and the role of tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Structure and function of claudins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Brain endothelial cell-cell junctions: how to "open" the blood brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Looking at the blood–brain barrier: Molecular anatomy and possible investigation approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Immunolocalization of tight junction proteins in the adult and developing human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Endocytosis of Epithelial Apical Junctional Proteins by a Clathrin-mediated Pathway into a Unique Storage Compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Endocytosis of the apical junctional complex: mechanisms and possible roles in regulation of epithelial barriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Caveolae-mediated internalization of occludin and claudin-5 during CCL2-induced tight junction remodeling in brain endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Expression of caveolin-1 in human brain microvessels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Caveolin-1 regulates expression of junction-associated proteins in brain microvascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Functions of lipid raft membrane microdomains at the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Expression of caveolin-1, -2, and -3 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Caveolin-1 regulates human immunodeficiency virus-1 Tat-induced alterations of tight junction protein expression via modulation of the Ras signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Up-regulation of caveolin-1 and blood-brain barrier breakdown are attenuated by N-acetylcysteine in thiamine deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

JRAB/MICAL-L2 is a junctional Rab13-binding protein mediating the endocytic recycling of occludin

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Formation of tight junction: determinants of homophilic interaction between classic claudins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

A peculiar internalization of claudins, tight junction-specific adhesion molecules, during the intercellular movement of epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Plasma membrane contributes to the formation of pre-autophagosomal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Regulation of the ischemia-induced autophagy-lysosome processes by nitrosative stress in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

The Beclin 1 network regulates autophagy and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

NG2 cells: Properties, progeny and origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Interplay between mechanisms of damage and repair in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Astrocytes and NG2-glia: what's in a name?

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

NG2+ CNS glial progenitors remain committed to the oligodendrocyte lineage in postnatal life and following neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Astrocyte-endothelial interactions at the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Epigenetic mechanisms facilitating oligodendrocyte development, maturation, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Importance of oligodendrocyte protection, BBB breakdown and inflammation for remyelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

An oligovascular niche: cerebral endothelial cells promote the survival and proliferation of oligodendrocyte precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Early contribution of pericytes to angiogenic sprouting and tube formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Pericyte deficiencies lead to aberrant tumor vascularizaton in the brain of the NG2 null mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

NG2 proteoglycan mediates beta1 integrin-independent cell adhesion and spreading on collagen VI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

β1-integrin/matrix interactions support blood-brain barrier integrity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

Erratum to “Clathrin-independent endocytosis: New insights into caveolae and non-caveolar lipid raft carriers” [Biochim. Biophys. Acta 1744 (2005) 273–286]

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E31826AC110

10.1097/NEN.0B013E31826AC110

21 January 2018

Identifiers

DOI

1 reference

11 February 2018

1 reference

11 February 2018