Effects of antemortem and postmortem variables on human brain mRNA quality: a BrainNet Europe study. (Q48379280)

11 February 2018

title

Effects of antemortem and postmortem variables on human brain mRNA quality: a BrainNet Europe study. (English)

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11 February 2018

author

Robert Walker

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Claire Troakes

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Miklós Palkovits

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11 February 2018

Inge Huitinga

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object named as

Inge Huitinga

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Thomas Arzberger

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object named as

Thomas Arzberger

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Jean-Jacques Hauw

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object named as

Jean-Jacques Hauw

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11 February 2018

author name string

Pascal F Durrenberger

1

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11 February 2018

Shama Fernando

2

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Samira N Kashefi

3

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Isidro Ferrer

4

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Danielle Seilhean

6

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Colin Smith

7

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Safa Al-Sarraj

9

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Magdalena Kasztner

12

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David T Dexter

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Hans Kretzschmar

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Richard Reynolds

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publication date

1 January 2010

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11 February 2018

Journal of Neuropathology & Experimental Neurology

published in

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11 February 2018

volume

69

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issue

1

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page(s)

70-81

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11 February 2018

Brain banking: opportunities, challenges and meaning for the future

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Quantification of mRNA degradation as possible indicator of postmortem interval—a pilot study

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Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain

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Assessing RNA quality in postmortem human brain tissue.

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Multivariate analysis of RNA levels from postmortem human brains as measured by three different methods of RT-PCR. Stanley Neuropathology Consortium.

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Critical factors in gene expression in postmortem human brain: Focus on studies in schizophrenia.

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Optimizing human post-mortem brain tissue gene expression profiling in Parkinson's disease and other neurodegenerative disorders: from target "fishing" to translational breakthroughs

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Gene expression profiling in the post-mortem human brain--no cause for dismay.

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Brain pH has a significant impact on human postmortem hippocampal gene expression profiles.

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Human postmortem tissue: what quality markers matter?

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Recovery and expression of messenger RNA from postmortem human brain tissue

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Postmortem delay has minimal effect on brain RNA integrity

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The RIN: an RNA integrity number for assigning integrity values to RNA measurements

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RNA integrity and the effect on the real-time qRT-PCR performance

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Hypoxia-inducible factor 1: regulation by hypoxic and non-hypoxic activators

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Comparison of relative mRNA quantification models and the impact of RNA integrity in quantitative real-time RT-PCR.

21 January 2018

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Impact of RNA degradation on gene expression profiles: assessment of different methods to reliably determine RNA quality.

21 January 2018

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Microarrays--the challenge of preparing brain tissue samples.

21 January 2018

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DNA chip technology in brain banks: confronting a degrading world.

21 January 2018

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21 January 2018

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Quality control for microarray analysis of human brain samples: The impact of postmortem factors, RNA characteristics, and histopathology.

21 January 2018

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Quantifying mRNA in postmortem human brain: influence of gender, age at death, postmortem interval, brain pH, agonal state and inter-lobe mRNA variance

21 January 2018

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High stability of mRNAs postmortem and protocols for their assessment by RT-PCR.

21 January 2018

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Effects of postmortem interval, age, and Alzheimer's disease on G-proteins in human brain.

21 January 2018

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Brain protein preservation largely depends on the postmortem storage temperature: implications for study of proteins in human neurologic diseases and management of brain banks: a BrainNet Europe Study.

21 January 2018

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21 January 2018

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21 January 2018

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10.1097/NEN.0B013E3181C7E32F

21 January 2018

Identifiers

DOI

1 reference

11 February 2018

PubMed ID

20010301

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11 February 2018