Phosphorylation sites on tau by tau protein kinase I, a bovine derived kinase generating an epitope of paired helical filaments (Q48395304)

11 February 2018

title

Phosphorylation sites on tau by tau protein kinase I, a bovine derived kinase generating an epitope of paired helical filaments (English)

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9 September 2022

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K. Ishiguro

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A. Omori

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M. Takamatsu

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K. Sato

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M. Arioka

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T. Uchida

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K. Imahori

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9 September 2022

language of work or name

English

0 references

publication date

1 December 1992

1 reference

11 February 2018

14 December 1992

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1284442

full work available at URL

9 September 2022

https://api.elsevier.com/content/article/PII:030439409290839Y?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

https://api.elsevier.com/content/article/PII:030439409290839Y?httpAccept=text/plain

23 November 2023

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

23 November 2023

1 reference

11 February 2018

volume

148

1 reference

11 February 2018

page(s)

202-206

1 reference

11 February 2018

issue

1-2

1 reference

11 February 2018

The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region

cites work

3

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

Tau protein binds to microtubules through a flexible array of distributed weak sites

23 November 2023

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1 reference

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Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

23 November 2023

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Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

23 November 2023

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1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs

23 November 2023

9

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains

23 November 2023

11

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease.

23 November 2023

12

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

A novel tubulin-dependent protein kinase forming a paired helical filament epitope on tau

23 November 2023

13

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

A serine/threonine proline kinase activity is included in the tau protein kinase fraction forming a paired helical filament epitope

23 November 2023

14

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

Fetal-type phosphorylation of the tau in paired helical filaments

23 November 2023

16

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

The carboxyl third of tau is tightly bound to paired helical filaments.

23 November 2023

17

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

Epitopes that span the tau molecule are shared with paired helical filaments.

23 November 2023

18

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

Implication of brain cdc2 and MAP2 kinases in the phosphorylation of tau protein in Alzheimer's disease.

23 November 2023

19

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

23 November 2023

20

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

Two novel kinases phosphorylate tau and the KSP site of heavy neurofilament subunits in high stoichiometric ratios

23 November 2023

21

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

A protein kinase associated with paired helical filaments in Alzheimer disease

23 November 2023

23

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

A protein factor essential for microtubule assembly

23 November 2023

24

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease

23 November 2023

25

1 reference

https://api.crossref.org/works/10.1016/0304-3940(92)90839-Y

23 November 2023

Identifiers

1 reference

11 February 2018

1 reference

11 February 2018