Growth impairment in IL-6-overexpressing transgenic mice is associated with induction of SOCS3 mRNA. (Q48400737)

11 February 2018

title

Growth impairment in IL-6-overexpressing transgenic mice is associated with induction of SOCS3 mRNA. (English)

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11 February 2018

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Jaroslava Lieskovska

1

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11 February 2018

Donglin Guo

series ordinal

2

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11 February 2018

Eva Derman

series ordinal

3

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11 February 2018

publication date

1 February 2003

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11 February 2018

Growth Hormone & I G F Research

published in

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11 February 2018

volume

13

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11 February 2018

issue

1

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11 February 2018

page(s)

26-35

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11 February 2018

Nucleotide sequences of liver, lachrymal, and submaxillary gland mouse major urinary protein mRNAs: mosaic structure and construction of panels of gene-specific synthetic oligonucleotide probes

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Identification of an enhancer required for the expression of a mouse major urinary protein gene in the submaxillary gland

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IL-6-overexpression brings about growth impairment potentially through a GH receptor defect.

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A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)

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The significance of tetramerization in promoter recruitment by Stat5.

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Negative regulation of cytokine signaling pathways

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7 January 2021

SOCS proteins, regulators of intracellular signaling

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7 January 2021

Twenty proteins containing a C-terminal SOCS box form five structural classes

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7 January 2021

A family of cytokine-inducible inhibitors of signalling

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7 January 2021

Structure and function of a new STAT-induced STAT inhibitor

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7 January 2021

Inhibition of Th1 Differentiation by IL-6 Is Mediated by SOCS1

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Role of the suppressor of cytokine signaling-3 in mediating the inhibitory effects of interleukin-1beta on the growth hormone-dependent transcription of the acid-labile subunit gene in liver cells

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Autoregulation of pituitary corticotroph SOCS-3 expression: characterization of the murine SOCS-3 promoter

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7 January 2021

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

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Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

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Bone homeostasis in growth hormone receptor-null mice is restored by IGF-I but independent of Stat5.

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Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice

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7 January 2021

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

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7 January 2021

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

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The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family

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Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

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IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP

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Convergence of TNFalpha and IFNgamma signalling pathways through synergistic induction of IRF-1/ISGF-2 is mediated by a composite GAS/kappaB promoter element

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7 January 2021

Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling

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7 January 2021

Intermittent plasma growth hormone triggers tyrosine phosphorylation and nuclear translocation of a liver-expressed, Stat 5-related DNA binding protein. Proposed role as an intracellular regulator of male-specific liver gene transcription

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7 January 2021

Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption.

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7 January 2021

SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms

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7 January 2021

Expression of six mouse major urinary protein genes in the mammary, parotid, sublingual, submaxillary, and lachrymal glands and in the liver

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Isolation of a cDNA clone for mouse urinary proteins: age- and sex-related expression of mouse urinary protein genes is transcriptionally controlled

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The gene family for major urinary proteins: expression in several secretory tissues of the mouse

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7 January 2021

Secretory rhythm of growth hormone regulates sexual differentiation of mouse liver

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7 January 2021

Human growth disorders: molecular genetics of the growth hormone-insulin-like growth factor I axis.

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7 January 2021

Interleukin 6 causes growth impairment in transgenic mice through a decrease in insulin-like growth factor-I. A model for stunted growth in children with chronic inflammation

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7 January 2021

Insulin like growth factor-I, insulin like growth factor binding protein-1, and insulin in childhood Crohn's disease

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7 January 2021

Diminished growth hormone-binding protein in children with insulin-dependent diabetes mellitus

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7 January 2021

Insulin-like growth factor-1, growth hormone-dependent insulin-like growth factor-binding protein and growth in children with chronic renal failure

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7 January 2021

CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation

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7 January 2021

SOCS3 is essential in the regulation of fetal liver erythropoiesis

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7 January 2021

Growth-hormone-receptor and cytokine-receptor-family signaling

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7 January 2021

SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985

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7 January 2021

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

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7 January 2021

Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation

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7 January 2021

Mutation of the SHP-2 Binding Site in Growth Hormone (GH) Receptor Prolongs GH-Promoted Tyrosyl Phosphorylation of GH Receptor, JAK2, and STAT5B

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7 January 2021

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

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7 January 2021

Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling

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7 January 2021

The JAK-STAT pathway: signal transduction involved in proliferation, differentiation and transformation

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7 January 2021

https://api.crossref.org/works/10.1016%2FS1096-6374%2802%2900135-1

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7 January 2021

Airway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivity

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7 January 2021

Growth hormone exerts antiapoptotic and proliferative effects through two different pathways involving nuclear factor-kappaB and phosphatidylinositol 3-kinase

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7 January 2021

SOCS-3 is an insulin-induced negative regulator of insulin signaling

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7 January 2021

Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor

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7 January 2021

SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

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7 January 2021

Role of insulin-like growth factors in embryonic and postnatal growth

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7 January 2021

Insulin-like growth factor-I affects perinatal lethality and postnatal development in a gene dosage-dependent manner: manipulation using the Cre/loxP system in transgenic mice.

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7 January 2021

10.1016/S1096-6374(02)00135-1

Identifiers

DOI

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11 February 2018

1 reference

11 February 2018