Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats. (Q48432340)

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scientific article published on 20 July 2012

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English	Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats.	scientific article published on 20 July 2012

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scholarly article

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/22821058

Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats. (English)

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/22821058

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triacylglycerol lipase inhibitor

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based on heuristic

inferred from title

Walter Balduini

9

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/22821058

author name string

Silvia Carloni

1

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/22821058

Daniel Alonso-Alconada

2

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/22821058

Silvia Girelli

3

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/22821058

Andrea Duranti

4

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/22821058

Andrea Tontini

5

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/22821058

Daniele Piomelli

6

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/22821058

Enrique Hilario

7

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/22821058

Antonia Alvarez

8

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11 February 2018

http://europepmc.org/abstract/MED/22821058

language of work or name

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publication date

20 July 2012

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11 February 2018

http://europepmc.org/abstract/MED/22821058

Pediatric Research

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http://europepmc.org/abstract/MED/22821058

72

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http://europepmc.org/abstract/MED/22821058

4

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/22821058

400-406

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11 February 2018

http://europepmc.org/abstract/MED/22821058

https://scigraph.springernature.com/pub.10.1038/pr.2012.91

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An endogenous cannabinoid (2-AG) is neuroprotective after brain injury

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The cannabinoid agonist WIN55212 reduces brain damage in an in vivo model of hypoxic-ischemic encephalopathy in newborn rats.

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The cannabinoid receptor agonist WIN 55,212-2 reduces the initial cerebral damage after hypoxic-ischemic injury in fetal lambs

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Extended role of necrotic cell death after hypoxia-ischemia-induced neurodegeneration in the neonatal rat

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Long-lasting behavioral alterations following a hypoxic/ischemic brain injury in neonatal rats

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Melatonin protects from the long-term consequences of a neonatal hypoxic-ischemic brain injury in rats

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Simvastatin protects against long-lasting behavioral and morphological consequences of neonatal hypoxic/ischemic brain injury

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Endocannabinoids mediate neuroprotection after transient focal cerebral ischemia

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RNA interference suggests a primary role for monoacylglycerol lipase in the degradation of the endocannabinoid 2-arachidonoylglycerol

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Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus

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An endocannabinoid mechanism for stress-induced analgesia.

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URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.

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The inhibition of monoacylglycerol lipase by URB602 showed an anti-inflammatory and anti-nociceptive effect in a murine model of acute inflammation

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The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines

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Endocannabinoid 2-arachidonoylglycerol protects neurons by limiting COX-2 elevation

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The influence of immaturity on hypoxic‐ischemic brain damage in the rat

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Design, synthesis, and structure-activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors.

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Identifiers

10.1038/PR.2012.91

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/22821058

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/22821058

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