Thymol improves high-fat diet-induced cognitive deficits in mice via ameliorating brain insulin resistance and upregulating NRF2/HO-1 pathway (Q48470200)

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scientific article published on 20 October 2016

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English	Thymol improves high-fat diet-induced cognitive deficits in mice via ameliorating brain insulin resistance and upregulating NRF2/HO-1 pathway	scientific article published on 20 October 2016

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27761760

Thymol improves high-fat diet-induced cognitive deficits in mice via ameliorating brain insulin resistance and upregulating NRF2/HO-1 pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27761760

insulin resistance

1 reference

based on heuristic

inferred from title

author name string

FangFang

1

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27761760

Hongyan Li

2

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27761760

Tingting Qin

3

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27761760

Min Li

4

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27761760

Shiping Ma

5

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27761760

publication date

20 October 2016

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Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27761760

Metabolic Brain Disease

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27761760

32

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27761760

2

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27761760

385-393

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27761760

Prolonged metformin treatment leads to reduced transcription of Nrf2 and neurotrophic factors without cognitive impairment in older C57BL/6J mice

1 reference

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21 January 2018

High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice

1 reference

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Cognitive-enhancing activity of thymol and carvacrol in two rat models of dementia

1 reference

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The source of cerebral insulin

1 reference

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21 January 2018

Hippocampal insulin resistance and cognitive dysfunction

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Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding

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The signaling mechanisms of hippocampal endoplasmic reticulum stress affecting neuronal plasticity-related protein levels in high fat diet-induced obese rats and the regulation of aerobic exercise

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The worldwide epidemiology of type 2 diabetes mellitus--present and future perspectives

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Rosiglitazone activation of PPARγ-dependent pathways is neuroprotective in human neural stem cells against amyloid-beta-induced mitochondrial dysfunction and oxidative stress.

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Inhibition of mitochondrial cytochrome c oxidase potentiates Aβ-induced ER stress and cell death in cortical neurons

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Urea-induced ROS generation causes insulin resistance in mice with chronic renal failure.

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Thymol produces an antidepressant-like effect in a chronic unpredictable mild stress model of depression in mice

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High-fat diets, insulin resistance and declining cognitive function

1 reference

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21 January 2018

Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity

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Polydatin improves glucose and lipid metabolism in experimental diabetes through activating the Akt signaling pathway.

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Hesperidin attenuates learning and memory deficits in APP/PS1 mice through activation of Akt/Nrf2 signaling and inhibition of RAGE/NF-κB signaling.

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Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52.

1 reference

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Increased Alzheimer's disease-like pathology in the APP/ PS1ΔE9 mouse model lacking Nrf2 through modulation of autophagy

1 reference

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21 January 2018

Nuclear Mechanisms of Insulin Resistance.

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Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

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Involvement of the Nrf2/HO-1 signaling pathway in sulfuretin-induced protection against amyloid beta25-35 neurotoxicity

1 reference

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21 January 2018

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

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miR-302 Attenuates Amyloid-β-Induced Neurotoxicity through Activation of Akt Signaling

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15d-PGJ2 stimulates HO-1 expression through p38 MAP kinase and Nrf-2 pathway in rat vascular smooth muscle cells.

1 reference

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Neuroprotective effect of paeonol on cognition deficits of diabetic encephalopathy in streptozotocin-induced diabetic rat.

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Comparative antioxidant properties of some GABAergic phenols and related compounds, determined for homogeneous and membrane systems

1 reference

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21 January 2018

Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity

1 reference

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21 January 2018

Antibacterial and efflux pump inhibitors of thymol and carvacrol against food-borne pathogens.

1 reference

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21 January 2018

Shared links between type 2 diabetes mellitus and Alzheimer's disease: A review.

1 reference

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21 January 2018

Increased risk of cognitive impairment in patients with diabetes is associated with metformin

1 reference

https://api.crossref.org/works/10.1007%2FS11011-016-9921-Z

21 January 2018

Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes.

1 reference

https://api.crossref.org/works/10.1007%2FS11011-016-9921-Z

21 January 2018

High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling

1 reference

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21 January 2018

Aβ-Induced Insulin Resistance and the Effects of Insulin on the Cholesterol Synthesis Pathway and Aβ Secretion in Neural Cells

1 reference

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Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats

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21 January 2018

GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

1 reference

https://api.crossref.org/works/10.1007%2FS11011-016-9921-Z

21 January 2018

Effects of metformin on learning and memory behaviors and brain mitochondrial functions in high fat diet induced insulin resistant rats.

1 reference

https://api.crossref.org/works/10.1007%2FS11011-016-9921-Z

21 January 2018

PPARγ agonist improves neuronal insulin receptor function in hippocampus and brain mitochondria function in rats with insulin resistance induced by long term high-fat diets.

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Protective effect of thymol on high fat diet induced diabetic nephropathy in C57BL/6J mice

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Glucose oxidase induces insulin resistance via influencing multiple targets in vitro and in vivo: The central role of oxidative stress

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Asiaticoside attenuates diabetes-induced cognition deficits by regulating PI3K/Akt/NF-κB pathway

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Protective effect of puerarin against beta-amyloid-induced oxidative stress in neuronal cultures from rat hippocampus: involvement of the GSK-3β/Nrf2 signaling pathway

1 reference

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Effect of thyme oil and thymol dietary supplementation on the antioxidant status and fatty acid composition of the ageing rat brain

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymol inhibits LPS-stimulated inflammatory response via down-regulation of NF-κB and MAPK signaling pathways in mouse mammary epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27761760

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11011-016-9921-Z

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27761760

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/27761760

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