Effects of proNGF on neuronal viability, neurite growth and amyloid-beta metabolism (Q48485675)

11 February 2018

title

Effects of proNGF on neuronal viability, neurite growth and amyloid-beta metabolism (English)

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11 February 2018

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16

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11 February 2018

Yan-Jiang Wang

Yan-Jiang Wang

1

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Wei Ping Gai

14

Wei-Ping Gai

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11 February 2018

Chang-Yue Gao

9

Chang-Yue Gao

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11 February 2018

Xiao-Hong Liu

6

Xiao-Hong Liu

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11 February 2018

Deborah Valadares

2

Deborah Valadares

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11 February 2018

Shohreh Majd

7

Shohreh Majd

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11 February 2018

Ernest A. Salegio

13

Ernest A Salegio

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11 February 2018

author name string

Ying Sun

3

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11 February 2018

Xin Wang

4

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11 February 2018

Jin-Hua Zhong

5

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11 February 2018

Li Chen

8

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11 February 2018

Si Chen

10

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11 February 2018

Yoon Lim

11

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11 February 2018

Anthony Pollard

12

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11 February 2018

Miao Yang

15

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11 February 2018

publication date

13 August 2009

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11 February 2018

published in

Neurotoxicity Research

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11 February 2018

volume

17

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11 February 2018

issue

3

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11 February 2018

page(s)

257-267

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11 February 2018

Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12640-009-9098-X

Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12640-009-9098-X

A TrkA-to-p75NTR molecular switch activates amyloid beta-peptide generation during aging

21 January 2018

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12 December 2020

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

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12 December 2020

Neurotrophins: roles in neuronal development and function

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12 December 2020

Neuroanatomical evidence for a cholinergic deficit in Alzheimer's disease

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12 December 2020

p75 neurotrophin receptor protects primary cultures of human neurons against extracellular amyloid beta peptide cytotoxicity.

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12 December 2020

Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins.

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12 December 2020

Fibrillar beta-amyloid (Abeta) (1-42) elevates extracellular Abeta in cultured hippocampal neurons of adult rats

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12 December 2020

Isolation and culture of adult neurons and neurospheres

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12 December 2020

Interactions between beta-amyloid and central cholinergic neurons: implications for Alzheimer's disease

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12 December 2020

Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system

1 reference

12 December 2020

Beta-amyloid plaques in a model for sporadic Alzheimer's disease based on transgenic anti-nerve growth factor antibodies

1 reference

12 December 2020

Intramuscular delivery of a single chain antibody gene reduces brain Abeta burden in a mouse model of Alzheimer's disease

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12 December 2020

ProNGF, sortilin, and age-related neurodegeneration

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12 December 2020

ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury

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12 December 2020

The beta-amyloid protein of Alzheimer's disease increases neuronal CRMP-2 phosphorylation by a Rho-GTP mechanism

1 reference

12 December 2020

Consumption of grape seed extract prevents amyloid-beta deposition and attenuates inflammation in brain of an Alzheimer's disease mouse

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12 December 2020

Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury

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12 December 2020

The common neurotrophin receptor p75NTR enhances the ability of PC12 cells to resist oxidative stress by a trkA-dependent mechanism

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12 December 2020

The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease

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12 December 2020

The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI.

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12 December 2020

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

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12 December 2020

Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives

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12 December 2020

Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease

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12 December 2020

Does the p75 neurotrophin receptor mediate Abeta-induced toxicity in Alzheimer's disease?

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12 December 2020

Regulation of cell survival by secreted proneurotrophins

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12 December 2020

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12 December 2020

The expression of p75 neurotrophin receptor protects against the neurotoxicity of soluble oligomers of beta-amyloid

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12 December 2020

Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice

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12 December 2020

Differential actions of neurotrophins on apoptosis mediated by the low affinity neurotrophin receptor p75NTR in immortalised neuronal cell lines.

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12 December 2020

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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12 December 2020

Axon growth inhibition: signals from the p75 neurotrophin receptor

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12 December 2020

Pro-NGF secreted by astrocytes promotes motor neuron cell death

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12 December 2020

Synaptic slaughter in Alzheimer's disease

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12 December 2020

Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice.

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12 December 2020

Ganstigmine and donepezil improve neurodegeneration in AD11 antinerve growth factor transgenic mice

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12 December 2020

In situ hybridization detection of trkA mRNA in brain: distribution, colocalization with p75NGFR and up-regulation by nerve growth factor

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12 December 2020

Pro-NGF from Alzheimer's disease and normal human brain displays distinctive abilities to induce processing and nuclear translocation of intracellular domain of p75NTR and apoptosis

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12 December 2020

Sortilin is essential for proNGF-induced neuronal cell death

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12 December 2020

Pathophysiological mechanisms for actions of the neurotrophins

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12 December 2020

Beta-amyloid(1-42) induces neuronal death through the p75 neurotrophin receptor.

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12 December 2020

Human ProNGF: biological effects and binding profiles at TrkA, P75NTR and sortilin

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12 December 2020

ProNGF inhibits NGF-mediated TrkA activation in PC12 cells

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12 December 2020

10.1007/S12640-009-9098-X

Identifiers

DOI

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11 February 2018

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11 February 2018