Brain uptake of nonsteroidal anti-inflammatory drugs: ibuprofen, flurbiprofen, and indomethacin. (Q48529548)

12 February 2018

title

Brain uptake of nonsteroidal anti-inflammatory drugs: ibuprofen, flurbiprofen, and indomethacin. (English)

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12 February 2018

author name string

Jagan Mohan R Parepally

series ordinal

1

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12 February 2018

Haritha Mandula

series ordinal

2

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12 February 2018

Quentin R Smith

series ordinal

3

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12 February 2018

publication date

2 May 2006

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12 February 2018

published in

Pharmaceutical Research

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12 February 2018

volume

23

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12 February 2018

issue

5

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12 February 2018

page(s)

873-881

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12 February 2018

Stereoselective disposition of ibuprofen enantiomers in human cerebrospinal fluid

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The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer's type.

21 January 2018

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Influence of molecular lipophilicity on the diffusion of arylpropionate non-steroidal anti-inflammatory drugs into the cerebrospinal fluid

21 January 2018

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12 December 2020

Brain perfusion systems for studies of drug uptake and metabolism in the central nervous system

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12 December 2020

Structural and functional aspects of the blood-brain barrier.

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Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport

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Molecular features, regulation, and function of monocarboxylate transporters: implications for drug delivery

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Determinants of passive drug entry into the central nervous system

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Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier

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12 December 2020

Drug entry into the brain

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12 December 2020

Effect of plasma protein binding on kinetics of capillary uptake and efflux.

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12 December 2020

Uptake of valproic acid into rat brain is mediated by a medium-chain fatty acid transporter.

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12 December 2020

Homeostatic capabilities of the choroid plexus epithelium in Alzheimer's disease

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12 December 2020

Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport systems

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12 December 2020

NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo

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12 December 2020

Molecular aspects of renal anionic drug transport

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12 December 2020

Altered brain penetration of diclofenac and mefenamic acid, but not acetaminophen, in Shiga-like toxin II-treated mice

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12 December 2020

Drug-protein binding and blood-brain barrier permeability

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12 December 2020

Inefficient central nervous system delivery limits the use of ibuprofen in neurodegenerative diseases.

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12 December 2020

Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity

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12 December 2020

An in situ brain perfusion technique to study cerebrovascular transport in the rat.

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12 December 2020

Development of a computational approach to predict blood-brain barrier permeability

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12 December 2020

Involvement of multispecific organic anion transporter, Oatp14 (Slc21a14), in the transport of thyroxine across the blood-brain barrier

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12 December 2020

Non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease: old and new mechanisms of action

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12 December 2020

Improved brain delivery of a nonsteroidal anti-inflammatory drug with a synthetic glyceride ester: a preliminary attempt at a CNS drug delivery system for the therapy of Alzheimer's disease.

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12 December 2020

Drug equilibration across the blood-brain barrier--pharmacokinetic considerations based on the microdialysis method

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12 December 2020

A review of blood-brain barrier transport techniques

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12 December 2020

Choosing the right nonsteroidal anti-inflammatory drug for the right patient: a pharmacokinetic approach

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12 December 2020

Blood-brain barrier penetration abolished by N-methyl quaternization of nicotine

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12 December 2020

In silico prediction of blood–brain barrier permeation

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12 December 2020

Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease

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12 December 2020

Quantitative evaluation of the drug-drug interactions between methotrexate and nonsteroidal anti-inflammatory drugs in the renal uptake process based on the contribution of organic anion transporters and reduced folate carrier

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12 December 2020

In vitro study of the functional expression of organic anion transporting polypeptide 3 at rat choroid plexus epithelial cells and its involvement in the cerebrospinal fluid-to-blood transport of estrone-3-sulfate

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12 December 2020

Clinical pharmacokinetics of nonsteroidal anti-inflammatory drugs in the cerebrospinal fluid

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12 December 2020

Participation of a proton-cotransporter, MCT1, in the intestinal transport of monocarboxylic acids.

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12 December 2020

A strategy for increasing the brain uptake of a radioligand in animals: use of a drug that inhibits plasma protein binding

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12 December 2020

Active efflux across the blood-brain barrier: role of the solute carrier family

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12 December 2020

10.1007/S11095-006-9905-5

Identifiers

DOI

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12 February 2018

release_e6ibljwo55emrecu7pr7r4lvjm

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/e6ibljwo55emrecu7pr7r4lvjm

24 November 2022

mapped directly with Wikidata item

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12 February 2018