In vivo electroporation of a new gene vaccine encoding ten repeats of Aβ3-10 prevents brain Aβ deposition and delays cognitive impairment in young Tg-APPswe/PSEN1dE9 mice (Q48603497)

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scientific article published on 22 March 2012

Language	Label	Description	Also known as
English	In vivo electroporation of a new gene vaccine encoding ten repeats of Aβ3-10 prevents brain Aβ deposition and delays cognitive impairment in young Tg-APPswe/PSEN1dE9 mice	scientific article published on 22 March 2012

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

In vivo electroporation of a new gene vaccine encoding ten repeats of Aβ3-10 prevents brain Aβ deposition and delays cognitive impairment in young Tg-APPswe/PSEN1dE9 mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

electroporation

1 reference

based on heuristic

inferred from title

cognitive dysfunction

1 reference

based on heuristic

inferred from title

author name string

Sha Sha

1

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

Xiao-Na Xing

2

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

Wan-Shu Guo

3

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

Yu Li

4

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

Li-Xia Zong

5

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

Rong Guo

6

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

Yun-Peng Cao

7

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

publication date

22 March 2012

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

Neurochemical Research

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

37

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Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

7

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

1534-1544

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

Alzheimer's disease: the amyloid cascade hypothesis

1 reference

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Dendrimeric Abeta1-15 is an effective immunogen in wildtype and APP-tg mice

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Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis.

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Conformation-sensitive antibodies against alzheimer amyloid-beta by immunization with a thioredoxin-constrained B-cell epitope peptide

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Generation of auto-antibodies towards Alzheimer's disease vaccination.

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Vaccination of Alzheimer's model mice with adenovirus vector containing quadrivalent foldable Abeta(1-15) reduces Abeta burden and behavioral impairment without Abeta-specific T cell response

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Antigen presentation and DNA vaccines

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21 January 2018

Adenovirus-based genetic vaccines for biodefense

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21 January 2018

Immunization of Alzheimer model mice with adenovirus vectors encoding amyloid beta-protein and GM-CSF reduces amyloid load in the brain

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21 January 2018

A novel recombinant adeno-associated virus vaccine reduces behavioral impairment and beta-amyloid plaques in a mouse model of Alzheimer's disease

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21 January 2018

Enhancement of DNA vaccine potency in rhesus macaques by electroporation

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21 January 2018

Gene transfer into muscle by electroporation in vivo.

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21 January 2018

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

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21 January 2018

Zinc overload enhances APP cleavage and Aβ deposition in the Alzheimer mouse brain

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Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

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21 January 2018

Will anti-amyloid therapies work for Alzheimer's disease?

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Melatonin biosynthesis and metabolism in peripheral blood mononuclear leucocytes

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21 January 2018

Melatonin as a pharmacological agent against neuronal loss in experimental models of Huntington's disease, Alzheimer's disease and parkinsonism

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21 January 2018

Melatonin as an adjuvant to therapeutic prostate cancer vaccines

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21 January 2018

DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model.

1 reference

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21 January 2018

Intramuscular delivery of a single chain antibody gene reduces brain Abeta burden in a mouse model of Alzheimer's disease

1 reference

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21 January 2018

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

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21 January 2018

Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration

1 reference

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21 January 2018

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

1 reference

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21 January 2018

Disaggregation of Alzheimer beta-amyloid by site-directed mAb.

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Immune function of astrocytes

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Endogenous IL-4 and IFN-γ are essential for expression of Th2, but not Th1 cytokine message during the early differentiation of human CD4+ T helper cells

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Monocyte-mediated suppression of IL-2-induced NK-cell activation. Regulation by 5-HT1A-type serotonin receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22437434

12 December 2020

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Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model

1 reference

https://pubmed.ncbi.nlm.nih.gov/22437434

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11064-012-0748-7

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 February 2018

http://europepmc.org/abstract/MED/22437434

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